Pages

Showing posts with label Sperm Quality. Show all posts
Showing posts with label Sperm Quality. Show all posts

Wednesday, 16 October 2019

Lycopene Has Been Found to Boost Sperm Quantity and Quality

While infertility is commonly thought of as a female problem, men too can experience fertility problems. Male infertility can have numerous causes, such as abnormal sperm production, genetic defects, undescended testicles, or certain health problems like gonorrhea, chlamydia, or HIV. 
In some instances, the underlying cause of poor sperm count or sperm quality cannot be determined. According to Mayo Clinic, a low sperm count (oligospermia) occurs when you have fewer than 15 million sperm per milliliter of semen. Having a low sperm count can significantly reduce the chance of one of your sperm fertilizing your partner’s egg, which is necessary for a successful pregnancy.
Lycopene and Its Effect on Male Fertility
A recent study conducted by scientists at the University of Sheffield states that the red pigment compound found in sun-ripened tomatoes can increase sperm count by up to 70% while providing other key benefits for male reproductive systems. About one in every six couples have difficulty conceiving. It is believed that poor sperm quality is to blame for about half of these cases. Lycopene, the red pigment found in tomatoes, has the potential to raise sperm quantity and quality.
Lycopene is a type of carotenoid, a naturally-occurring pigment that gives some fruits and vegetables their red color. You can find lycopene in watermelons, red carrots, and papayas, but not in certain red crops like cherries and strawberries. It is particularly present in high amounts in tomatoes. In fact, tomatoes offer about 80 percent of the lycopene in the typical U.S. diet. One serving of fresh tomatoes provides between 4 and 10 mg of lycopene, while one cup of tomato juice has about 20 mg. Lycopene can also be found in supplement form, although the raw product is easier for the body to use.
Adding Lycopene to Your Everyday Diet
If the thought of eating tomatoes for every meal sounds repulsive, don’t fret. There are many delicious ways to increase the amount of lycopene in your diet without having to eat raw tomatoes at every meal. Like any nutrient, lycopene should not be overconsumed. Currently, there is no official recommended amount for daily intake of lycopene. However, in a report published in International Urology and Nephrology Journal in which men with impaired fertility were given 2 mg of lycopene twice a day, 66 percent saw improved sperm concentration and 53 percent had improved mobility.
There are countless ways to incorporate more lycopene into your diet, such as:
  • Fresh-squeezed tomato juice
  • Tropical fruit smoothie with fresh tomatoes
  • Homemade pizza sauce
  • Spaghetti sauce served over whole grain pasta or eggplant
  • Tomato slices added to sandwiches or salads
  • Bruschetta created with freshly chopped tomatoes
  • Pureed tomato in soups or stews
  • Homemade salsa spooned over scrambled eggs
  • Baked stuffed tomatoes with meat and cheese
The Sperm Count Regeneration Cycle
It is important to understand that eating tomatoes for a few days will not instantly solve your fertility woes. Although you produce new sperm every day, it takes time for the reproductive system to complete a full sperm regeneration cycle, a process known as spermatogenesis. During spermatogenesis, the testicles regenerate new, functional sperm. In addition to consuming more lycopene-rich foods, you can improve the quality and quantity of your sperm by exercising regularly, limiting smoking and alcohol intake, wearing loose-fitting underwear and clothing, and maintaining a vitamin-rich diet.
https://legacyivf.com/lycopene-has-been-found-to-boost-sperm-quantity-and-quality/

Why tomato puree might improve male fertility

Lycopene - a nutrient found in tomatoes - may boost sperm quality, a study has suggested.

9 October 2019
Tomato pureeImage copyrightGETTY IMAGES
Lycopene - a nutrient found in tomatoes - may boost sperm quality, a study has suggested.
Healthy men who took the equivalent of two tablespoons of (concentrated) tomato puree a day as a supplement were found to have better quality sperm.
Male infertility affects up to half of couples who cannot conceive.
Fertility experts said more studies were needed involving men known to have fertility problems.
NHS advice for men experiencing fertility problems currently suggests they adopt a healthy lifestyle and wear loose-fitting underwear.
It also suggests reducing stress as much as possible and ensuring they have regular sex around the time their partner ovulates to maximise the chances of conception.
But the idea that certain nutrients could boost male fertility has been gaining ground for some time.
Lycopene, like vitamin E and zinc which have been the focus of previous research, is an antioxidant which means it prevents oxidation in cells, and therefore damage.
It has been linked to other health benefits, including reducing the risk of heart disease and some cancers.
Cooked tomatoesImage copyrightGETTY IMAGES
The Sheffield team say they used a lactolycopene supplement because the nutrient in food can be harder for the body to absorb and so they could be confident each man received the same amount each day.

The men would have needed to eat 2kg of cooked tomatoes each day to get the equivalent dose of lycopene.

'Very encouraging'

In the 12-week trial, which was partly funded by the company which makes the supplement, 60 men were randomly selected to take 14 milligrams of lactolycopene per day or a dummy pill.
Their sperm was tested at the start, at six weeks and at the end of the study, and while there was no difference in sperm concentration, the proportion of healthy-shaped sperm and motility - how fast sperm can "swim" - was higher in those taking lycopene.
Dr Liz Williams, a specialist in human nutrition at the University of Sheffield, who led the research which was published in the European Journal of Nutrition, said: "At the moment, there is very little advice we can give to men.
"We tell them to reduce alcohol consumption and eat a healthy diet - but these are very general messages."
She added: "This was a small study and we do need to repeat the work in bigger trials, but the results are very encouraging.
"The next step is to repeat the exercise in men with fertility problems and see if lycopene can increase sperm quality for those men and whether it helps couples conceive and avoid invasive fertility treatments."
Andrew Drakeley, clinical director at Liverpool Women's Hospital's Hewitt Fertility Centre, said: "Optimising the health of the subfertile couple, both male and female can often avoid the need for invasive and expensive fertility treatment."
But he said: "Further work in a subfertile population, demonstrating improved fecundity is needed before the treatment can be recommended."
Gwenda Burns, of the charity Fertility Network, added: "Although in the very early stages, this study offers hope for improvement of sperm quality and a greater understanding of male fertility in the future."

More on this story


Related Internet links


https://www.bbc.com/news/health-49971247

Tomatoes discovered to boost sperm quality

Dietary supplement from tomatoes discovered to boost sperm quality

Date:
October 9, 2019
Source:
University of Sheffield
Summary:
Sperm quality can be improved with a simple diet supplement containing a compound found in cooked tomatoes, according to new research.
FULL STORY

Sperm quality can be improved with a simple diet supplement containing a compound found in cooked tomatoes, according to new research by the University of Sheffield.
Image result for tomatoes improve sperm count
The discovery could transform the outlook for men with fertility problems and lead to better ways to reduce the damaging impact of modern living on reproductive health. Of all infertility cases, approximately 40 to 50 per cent are due to "male factor" infertility.
The first ever double-blind randomised controlled trial to assess the impact of giving men a dietary compound called LactoLycopene, was led by Allan Pacey, Professor of Andrology Reproduction and Head of the University of Sheffield's Department of Oncology and Metabolism, and Dr Liz Williams, a leading specialist in Human Nutrition at the University of Sheffield. The team discovered it is possible to increase the proportion of healthy shaped sperm (sperm morphology) and boost 'fast swimming' sperm by around 40 per cent.
Lycopene can be found in some fruits and vegetables, but the main source in the diet is from tomatoes. Lycopene is a pigment that gives tomatoes their red colour, but dietary Lycopene is poorly absorbed by the human body, so the compound used for the trial was a commercially available formulation called LactoLycopene; designed by FutureYou Cambridge to improve bioavailability.
The 12-week trial designed by Dr Williams involved 60 healthy volunteers aged 19 to 30. Half took LactoLycopene supplements and the other half took identical placebo (dummy pills) every day for 12 weeks. Neither the researchers nor the volunteers knew who was receiving the LactoLycopene treatment and who was receiving the placebo. Sperm and blood samples were collected at the beginning and end of the trial.
"We didn't really expect that at the end of the study there would be any difference in the sperm from men who took the tablet versus those who took the placebo. When we decoded the results, I nearly fell off my chair," said Professor Pacey, a world expert in male reproduction.
"The improvement in morphology -- the size and shape of the sperm, was dramatic. We used a computer system to make these measurements, which takes a lot of the human error out of the results. Also, the person using the computer didn't know who had taken LactoLycopene and who had taken the dummy pills either.
"This was the first properly designed and controlled study of the effect of LactoLycopene on semen quality, and it has spurred us to want to do more work with this molecule."
"We were surprised by the improvement in sperm quality shown by the results," said Dr Williams.
"This was a small study and we do need to repeat the work in bigger trials, but the results are very encouraging. The next step is to repeat the exercise in men with fertility problems and see if LactoLycopene can increase sperm quality for those men and whether it helps couples conceive and avoid invasive fertility treatments."
Her team, which included three other researchers Madeleine Park, Aisling Robinson and Sophie Pitt, is hoping to embark on the new study as soon as possible.
Professor Pacey said the work so far has not investigated the mechanism for Lycopene's beneficial action but it is a known powerful antioxidant, so is potentially inhibiting the damage caused by oxidation of sperm which is a known cause of male fertility problems. He believes this antioxidant effect is key in producing the improvements in sperm quality seen in the trial, and is hoping to investigate this more.

Story Source:
Materials provided by University of SheffieldNote: Content may be edited for style and length.

Journal Reference:
  1. Elizabeth A. Williams, Madeleine Parker, Aisling Robinson, Sophie Pitt, Allan A. Pacey. A randomized placebo-controlled trial to investigate the effect of lactolycopene on semen quality in healthy malesEuropean Journal of Nutrition, 2019; DOI: 10.1007/s00394-019-02091-5

https://www.sciencedaily.com/releases/2019/10/191009101159.htm

EATING TOMATOES COULD IMPROVE SPERM QUALITY BY UP TO 50 PER CENT, SCIENTISTS CLAIM

A compound found in tomatoes could help tackle fertility problems in men, scientists claim.
A new study of a small cohort of men has found that the pigment which gives the fruit its red colour, known as lycopene, could boost sperm quality, specifically around size and swimming capabilities.
10 October 2019

Image result for tomatoes improve sperm count
Researchers credit ingredient which gives the fruit its bright red colour 
The researchers say their findings could help reduce the need for invasive fertility treatments in the future as more than 40 per cent of all infertility cases are due to abnormal sperm production or function.

For the study, the team from the University of Sheffield recruited 60 healthy volunteers aged between 19 and 30. 
During the 12-week trial, half of the participants took 14mg of LactoLycopene – a pill created by supplement manufacturer Cambridge Nutraceuticals Ltd that contains the tomato pigment – while the other half took placebos.
The team analysed the sperm samples collected at the beginning and end of the trial.
The results, published in the European Journal of Nutrition, showed that participants taking LactoLycopene had almost 40 per cent more fast-swimming sperm than when they began the trial, along with improvements to size and shape.
Professor Allan Pacey, head of the University of Sheffield's department of oncology and metabolism and lead author, said: "We didn't really expect that at the end of the study there would be any difference in the sperm from men who took the tablet versus those who took the placebo.
"When we decoded the results, I nearly fell off my chair. The improvement in morphology - the size and shape of the sperm - was dramatic."
Pacey added that he believes the anti-oxidant properties of lycopene could prevent sperm from becoming damaged.
The team say that the next stage is to repeat the exercise in men with fertility issues to see if the supplement can increase sperm quality and whether or not it can help couples conceive without invasive fertility treatments.
Prof Richard Sharpe, a professor at MRC Centre for Reproductive Health at the University of Edinburgh, called the study a “small ray of sunshine”.
“The findings could mean that consumption of this tomato extract compound might have a beneficial effect in men with infertility because of poor sperm motility and/or morphology,” Sharpe said.
Commenting on the research, Ying Cheong, professor of Reproductive Medicine at the University of Southampton, recommended that the team expand on their findings with a study that uses “live birth” as the end point. 
“This study, undoubtedly, will add to our current knowledge of yet another anti-oxidant type supplement on sperm parameters, but what the study fails to tell us is if taking lactolycopene supplements improves fertility, that is the chance of actually having a successful pregnancy,” Cheong said. 
https://www.independent.co.uk/life-style/health-and-families/tomatoes-lycopene-sperm-quality-male-fertility-a9148516.html

Wednesday, 26 June 2019

Be in bed before 10.30 if you want to have kids, men told following new study linking lack of sleep to poor fertility

Men should get to bed before 10.30pm to improve their chances of fathering children, scientists have said following a groundbreaking new study.The data showed that tho...

sleep
Between seven and a half and eight hours sleep is ideal, the study says


Men should get to bed before 10.30pm to improve their chances of fathering children, scientists have said following a groundbreaking new study.
The data showed that those tucked up early had nearly four times greater sperm quality compared to those who went to sleep at 11.30 or later.
Fertility experts said they believe a lack of sleep provokes the immune system into overreacting and attacking healthy sperm.
It also puts men under physical and psychological stress, which is thought to further damage their chances of conceiving.
The team at Aarhus University in The Netherlands said the findings are increasingly significant in the age of Netflix where people tend to binge-watch television late into the night.
They studied 104 men with an average age of 34 over a two-year period, tracking their sleep patterns and comparing them against the results of sperm sample analysis.
The figures showed that even the difference between getting to sleep before 10.30 and between 10.30 and 11.30 yielded a 2.75-times greater healthiness of sperm.
Presented at the European Society of Human Reproduction and Embryology conference in Vienna, the study contributes to a growing shift in focus towards the impact of substandard sperm in couples’ infertility, a factor scientists now believe has been underestimated for years.
Professor Hans Jakob Ingerslev, who co-authored the study, said: “The reasons could be psychological as sleep-deprived men suffer more stress and that can have an impact on fertility.
“These were men who had been trying to have a baby for about two years and an early bedtime was likely to be important because it allowed them to get more sleep.”
As well as investigating the time at which aspiring fathers went to sleep, the team also assessed sleep duration against the health of the participants’ sperm.
They found that between seven and a half and eight hours sleep was ideal.
The sperm of men who slept this length appeared to be more than six times healthier than that of those who got less than seven hours.
However, no link was found between sperm health and sleeping for eight hours or longer.
Dr Christopher Barratt, professor of reproductive medicine at the University of Dundee, said: “If you don’t get enough sleep, that has an impact on the metabolism, which will have a negative effect on sperm quality.
He added: “It is pretty basic advice but a lack of sleep is closely tied to feeling stressed and stressed men are also less likely to have sex once a day, as we recommend when trying for a baby.”
The new research follows a recent study from Imperial College London, which discovered that the sperm of infertile men is every bit as healthy as that of fertile men while it is still in the testicles.
However, by the time it has travelled through a series of ducts and left the body it has become damaged, suggesting something toxic is happening along its path to the outside.
It is thought discovery offers new hope for men who struggle to become fathers even with the help of IVF.
https://www.telegraph.co.uk/news/2019/06/24/bed-1030-want-have-kids-men-told-following-new-study-linking/