By
Timothy Boyer
on February 1, 2012 - 12:32pm

for eMaxHealth

Bacterial infections from microbes such as MRSA pose a significant threat to
health as many antibiotics are ineffective in treating a growing number of
infections.
However, scientists recently reveal a new study that tells us that
an ancient Egyptian cure may be our best weapon against not just MRSA, but
potentially the majority of bacterial infections.
Discover what this cure is and why you should have it in your medicine
cabinet.
We are carriers of disease. Although the ancient Egyptians understanding may
not have been on the same level of understanding as it is today that one cause
of disease such as Methicillin-resistant Staphylococcus aureus (MRSA) is as
close to us as our skin, they nevertheless understood the importance of fighting
off infection.
According to PubMed Health, 1 out of every 4 healthy individuals carries a
strain of Staphylococcus aureus on their skin or in their nasal passages.
Furthermore, 2 out of every 100 people carry a strain of staph that is resistant
to antibiotics.
One of the misconceptions of antibiotic resistance is the belief that failure
of an infection to respond to an antibiotic means that the microbe has mutated
in some way that makes it resistant to a specific antibiotic or class of
antibiotics. However, recent research tells us that this is often not true.
Rather, that many types of bacteria produce protective biofilms that thwart an
antibiotic’s antimicrobial abilities.
A biofilm is a thin layer of microbes that sticks to the surface of a
structure such as a healing wound and is aided by organic polymers the microbes
secrete to insure adhesion as well as growth over the wound. Biofilms have
relatively recently been shown to form a type of protective barrier against
antibiotics.
However, it appears that some natural organic substances have a way of
breaking down the protective biofilm barrier and destroying the bacterial
colonies in an infection. One natural substance is mentioned in Ancient Egyptian
writing dating back 4,000 years that describes the practice of mixing honey on
cotton fibers and applying it on wounds as dressings.
The use of honey derived from some types of plants has been in use for a
number of years now and is available as a topical ointment to apply directly on
a wound. The most common source of honey is “Manuka Honey,” which is produced by
bees that collect nectar from the Manuka Bush or Tea Tree (Leptospermum
Scoparium) that is indigenous to New Zealand.
Exactly how Manuka honey works is currently under investigation, but it is
suspected to contain one or more ingredients with potent antibacterial,
antimicrobial, antiviral, antioxidant, antiseptic, anti-inflammatory and
anti-fungal properties.
Honey is a complex substance estimated to be comprised of several hundred
components, including fructose, glucose, sucrose and other sugars as well as
acids, proteins, amino acids , nitrogen, minerals, and in the case of Manuka
honey— methylglyoxal (MGO), which is believed to be crucial toward its
antimicrobial properties.
Researchers wanting to gain an understanding of how Manuka honey works on
infections decided to perform in-vitro tests on the effect of Manuka honey on
Streptococcus pyogenes bacteria that live in the nasopharynx and skin of healthy
individuals. S. pyogenes is a common infection problem in patients following
surgery and is known for its protective biofilm properties.
The goal of the researchers was to determine whether Manuka honey disrupted
the biofilm binding of S. pyogenes to human wound proteins called “fibrinogen”
and “fibronectin” that play an important role in the normal wound healing
process.
What they found as reported in the Jan. 31, 2012 issue of Microbiology, is
that treatment with Manuka honey resulted in not only inhibiting the development
of biofilms, but also disrupted established biofilms of S. pyogenes by possibly
interrupting the adhesion of tissue ligands related to fibronectin protein found
in wound healing. The exact molecular process remains unknown, but is believed
to involve a disruption of expression of fibronectin-binding proteins Sof and
SfbI from the S. pyogenes bacterium.
The authors concluded that their results add further support to the use of
Manuka honey in treating infection from S. pyogenes due to its ability to attack
the bacterium’s biofilm.
Their findings lend support to the treatment of other antibiotic resistant
microbes with biofilm components such as
MRSA
and other strains of infectious bacteria. Furthermore, this is yet another
example that there is value in investigating medical knowledge and practices
from other cultures even as far back as the days of the Ancient Egyptians.
Image Source: Courtesy of
Wikipedia
Reference:
“Manuka honey inhibits the development of Streptococcus pyogenes biofilms and
causes reduced expression of two fibronectin binding proteins” Microbiology
Jan.31, 2012; Sarah E. Maddocks, Marta Salinas Lopez, Richard S. Rowlands and
Rose A. Cooper
http://www.emaxhealth.com/8782/ancient-egyptian-cure-may-fight-mrsa-infections