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A study has found that when palmitic acid was supplemented into the diet of mice, mouth and skin cancers were more likely to spread. Palmitic acid, or palm oil has remained a controversial substance however this latest study shines a light on how it could be one of the main causes for the increase in cancer diagnosis seen of late.
Metastasis – or the spread – of cancer remains the main cause of death in cancer patients and the vast majority of people with metastatic cancer can only be treated, but not cured.
As most are aware, food can have a major impact on cancer with fatty acids being the building blocks of fat in the body.
Unfortunately, metastasis is often promoted by fatty acids in one’s diet further warning what you put in your mouth can have a devastating health impact.
Newly published findings, led by researchers at IRB Barcelona, Spain, reveal that one such fatty acid commonly found in palm oil, called palmitic acid, promotes metastasis in oral carcinomas and melanoma skin cancer in mice.
“There is something very special about palmitic acid that makes it an extremely potent promoter of metastasis,” said Prof Salvador Aznar-Benitah, of the Institute for Research in Biomedicine (IRB), Barcelona.
“I think it is too early to determine which type of diet could be consumed by patients with metastatic cancer that would slow down the metastatic process.”
The study suggested that exposure to palmitic acid caused changes to the function of genes in cancer cells that allowed them to sense fatty acids and consume them more efficiently.
The presence of palmitic acid also appeared to send cancer cells into a “regenerative state” allowing them to form signalling networks beyond the tumour, which is known to be a crucial step towards spreading.
Prof Greg Hannon, director of the Cancer Research UK Cambridge Institute, said: “This is a rigorous and comprehensive study that suggests that exposure to a major constituent of palm oil durably changes the behaviour of cancer cells, making them more prone to progress from local to potentially lethal metastatic disease.
“Given the prevalence of palm oil as an ingredient in processed foods, this study provides strong motivation for further study on how dietary choices influence the risk of tumour progression.”
Helen Rippon, chief executive at Worldwide Cancer Research, added: “This discovery is a huge breakthrough in our understanding of how diet and cancer are linked and, perhaps more importantly, how we can use this knowledge to start new cures for cancer.
Metastasis is estimated to be responsible for 90 percent of all cancer deaths – that’s around nine million deaths a year globally.
“Learning more about what makes cancer spread and – importantly – how to stop it is the way forward to reduce these numbers.”
Cancer is the second most common cause of death. It's more curable when detected earlier.
Although some cancers develop completely without symptoms, some do have signs you are likely to ignore.
Weight loss for no known reason, not through exercise or changes in diet is a common sign of cancers related to lung, stomach or pancreas.
Fever may be a sign of early cancer in the blood like leukemia and lymphoma. Fever may also reveal kidney and colon cancer at an early stage.
Extreme fatigue that cannot get better after rest can be a symptom of several cancer types such as leukemia, colon cancer, and stomach cancer.
Sometimes bone cancer or testicular cancer can cause pain. A headache that doesn't get better after a long-time treatment may be a symptom of a brain tumor. Back pain may be a sign of cancer in the ovary or colon.
Coughing up blood may be a sign of lung cancer. Blood in the stool or urine can forecast colon cancer or kidney or bladder cancer. A bloody discharge from the nipple can indicate breast cancer.
A lump that is usually hard, not painful, irregularly shaped or firmly attached deep in the soft tissue or under the skin is often caused by cancer.
More than half of people who have a cough that just wouldn't go away are diagnosed with lung cancer. Excessive coughing is also common signs of laryngeal and thyroid cancer.
Cancer in or near the lungs may cause a blockage of the tubes that carry air. Breathlessness is also common with breast cancer tumors, ovarian or liver cancer.
Mouth or throat cancers can make the swallowing difficult. It's also a common sign of various head and neck cancers such as esophageal, oropharyngeal cancer, thyroid, and laryngeal cancers.
Heartburn that doesn't go away or gets worse could mean cancer of the throat, stomach, or ovaries. Excessive food, alcohol, or stress can cause serious heartburn.
It rarely happens, but belly pain plus depression can be a sign of pancreatic cancer. But you don’t need to worry unless this disease runs deep in your family.
Any freckle, mole or wart that changes color, shape, or size should be examined for skin cancer. Besides, darker looking skin, reddened skin, itching, yellowish eyes, and skin may also be linked to cancers.
Long-term diarrhea, constipation or a change in the size of the stool can be a symptom of rectal or colon cancer. Pain when passing or blood in urine can be related to bladder or prostate cancer.
White patches inside the mouth can be leukoplakia, which is pre-cancerous and can become mouth cancer if it's not treated early.
Precancerous conditions of the genital or anal areas can cause persistent itching. If the itching continues with over-the-counter topical medications, consult your doctor.
Common sores usually heal quickly. If you have persistent sores in areas like your mouth, you may have cancer and should raise concerns and see a doctor.
https://www.buzzaura.com/12-cancer-symptoms-you-are-most-likely-to-ignore
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