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Showing posts with label HPB Singapore. Show all posts
Showing posts with label HPB Singapore. Show all posts

Thursday, 18 October 2012

Breast Cancer - Singapore Health Promotion Board

Source: Health Promotion Board, Singapore

Breast cancer is the most common cancer among women in Singapore. 1 in 17 women develops breast cancer in her lifetime. The risk of developing breast cancer increases with age. Breast cancer affects all women, it is the most prevalent in women age 50 years to 59 years in Singapore1.



Common types of breast cancer


The most common types of breast cancer begin either in the milk ducts (ductal carcinoma) or in the milk-producing glands (lobular carcinoma).

In situ breast cancer


In situ (noninvasive) breast cancer refers to cancer which has not spread to breast tissue around the duct or lobule.

Invasive breast cancer


  • Invasive ductal carcinoma (IDC) accounts for about 70 percent of all breast cancers.
  • Invasive lobular carcinoma (ILC) starts in the milk-producing lobules and then spreads into the surrounding breast tissue.

Symptoms


The commonest presentations of a breast cancer include:

BreastCancer_signs (image)

  • Breast lump
  • Bloody or unusual nipple discharge
  • Skin changes
  • Persistent rash around the nipple
  • Retracted nipple
  • Breast pain

Causes


As with most cancers, the exact cause for breast cancer is unknown.

Experts believe that it is multi-factorial involving a combination of genetic and environmental factors.

  • Inherited causes include some defects in the genes called breast cancer gene 1 (BRCA1) and breast cancer gene 2 (BRCA2) which are transmitted in families.
  • Some acquired causes include mutations in genes caused by exposure to radiation.

Risk factors


  • Age. The risk of developing breast cancer increases with age.
  • Personal history of breast cancer. The risk increases if the woman had breast cancer previously in one breast.
  • Family history of breast cancer in first degree relatives such as mother, sister or daughter.
  • Genetic predisposition. About 5-10% of breast cancers are inherited. Defects in genes such as BRCA1 or BRCA2 increase the risk of developing breast, ovarian and colon cancers.
  • Radiation exposure to chest in childhood or adolescence.
  • Early onset of menses and late menopause.
  • Hormone replacement therapy with a combination of estrogen and progesterone for four or more years.
  • Birth control pills. Use of pills for four years or more is associated with an increased risk of breast cancer.
  • Alcohol intake. Excessive consumption of alcohol (> one alcoholic beverage per day) increases the risk of developing breast cancer by 20%.

Diagnosis


See your doctor as soon as possible if you have:

  • Discovered a lump which persists.
  • Noticed a change in the appearance of the breast or discharge from the nipple.
  • Persistent bone aches lasting more than 3 weeks.

Common screening tests include:

  • Breast self examination.
  • Clinical breast examination to examine the breasts for lumps and to check the armpits for enlarged lymph nodes.
  • Screening mammograms which are done on a yearly basis to detect any lump or changes in the breasts.
  • Breast Ultrasound to determine if the lump is cystic or solid in structure.

Diagnostic procedures include:

  • Ultrasound is done to differentiate between a cyst and solid mass.
  • Fine needle aspiration biopsy involves using a thin, hollow needle to withdraw tissue from the lump for microscopic examination.
  • Core needle biopsy also involves taking tissue samples using a hollow needle from the lump for microscopic examination.
  • Surgical biopsy is the most reliable methods to confirm if the lump is cancerous.

Treatment


The three primary treatment options are: surgery, chemotherapy and radiation which may be used alone or in combination.

Surgery


Breast cancer operations include the following:

  • Lumpectomy involves removing only the lump of tumour plus a surrounding area of normal tissue.
  • Partial or segmental mastectomy involves removing the tumour as well as some of the breast tissue.
  • Simple mastectomy involves removal all the breast tissue.
  • Modified radical mastectomy involves removal of the entire breast, including the overlying skin and some underarm lymph nodes (axillary lymph nodes).

Radiation therapy


Radiation therapy uses high-energy X-rays to kill cancer cells and shrink tumors.

Chemotherapy


Chemotherapy uses drugs to destroy cancer cells.

Hormone therapy


Hormone therapy is often used to treat women whose cancers are sensitive to hormones. These include:

  • Selective estrogen receptor modulators (SERMs) such as tamoxifen.
  • Aromatase inhibitors include anastrozole, letrozole and exemestane.

Prevention


Chemoprevention


Chemoprevention is the use of medications to decrease breast cancer risk.

Two drugs used for breast cancer prevention in high-risk women include:

  • Tamoxifen
  • Raloxifene

Preventive surgery


Although a radical strategy, preventive surgery has been shown to reduce breast cancer risk in high-risk women.

Options include:

  • Prophylactic mastectomy in women who have cancer in one breast, a family history of breast cancer or carry BRCA1 or BRCA2 mutation.
  • Prophylactic oophorectomy. Although the procedure is usually performed to reduce ovarian cancer risk, oophorectomy has been shown to reduce the risk of breast cancer.

Lifestyle modifications


  • Limiting alcohol intake to less than one drink a day or avoiding alcohol completely.
  • Maintain a healthy weight as there is a clear link between obesity and breast cancer.
  • Avoid long-term hormone therapy.
  • Staying physically active.
  • Eating foods high in fiber such as fresh fruits, vegetables and whole grains.
  • Consuming more olive oil as oleic acid, the main component of olive oil, appears to suppress the action of some cancer related genes in breast cancer.

1Trends in cancer incidence in Singapore 1998-2002, Singapore Cancer Registry 2002


Source: Health Promotion Board, Singapore
www.spb.gov,sg

Stomach Cancer - Singapore Health Promotion Board



Source: Health Promotion Board, Singapore


Cancer of the stomach is the fifth most common cancer in men and the seventh most common cancer in women in Singapore.

Stomach cancer is readily treatable when diagnosed early.

The good news is that you can reduce your risk of stomach cancer by making a few changes in your lifestyle.



Types of stomach cancer


  1. Adenocarcinomas. Commonest type of cancer arising from the glandular cells in the stomach lining.
  2. Lymphomas. These arise from the lymphatic tissue (immune related tissues) in the stomach wall and are associated with H.Pylori infection.
  3. Carcinoid tumours are cancers arising from various hormone producing cells in the stomach lining.
  4. Gastrointestinal stromal tumours which arise from certain specialised cells in the nerve supply of the stomach.

Risk factors


Various risk factors for stomach cancer include:

  • Helicobacter pylori infection
  • Nitrates and nitrites are nitrogen based chemicals that are added to certain foods such as ham and bacon, hot dogs and deli meats.
  • Red meats and salted, pickled or smoked foods
  • Tobacco and alcohol use
  • Males have double the rate of stomach cancer compared to women
  • Stomach polyps
  • Previous stomach surgery
  • Family History
  • Pernicious anaemia

Signs & symptoms


Early signs of stomach cancer are bleeding which is usually detected by tests that check for blood in stool.

Other symptoms include:

  • Abdominal discomfort aggravated by eating or feeling full after eating small amounts of food
  • Heartburn
  • Black, tarry stools
  • Vomiting blood or after meals
  • Weight loss and loss of appetite

Screening & diagnosis


Simple diagnostic tests include:

  • Upper gastrointestinal Endoscopy. A thin lighted, flexible tube (endoscope) is inserted through your mouth into your food pipe and stomach.
  • Barium meal X-ray is done after the patient consumes a thick liquid (barium) which coats the lining of the food pipe, stomach and the first part of your intestine.
  • CT Scan (computerised tomography) and MRI (magnetic resonance imaging) tests.

Treatment


Stomach cancer treatment options include:

  • Surgery involves removal of part (subtotal or partial gastrectomy) or all (total gastrectomy) of the stomach.
  • Chemotherapy involves the use of cancer drugs which will kill the cancer cells.
  • Radiation therapy involves the use of high energy X-rays to kill cancer cells.

Prevention


If you are at high risk of developing stomach cancer, you may reduce your risk by taking a few measures which include:

  • Avoid foods such as processed meats which have a high content of nitrates and nitrites such corned beef.
  • Reduce your intake of smoked, pickled and heavily salted foods.
  • Avoid smoking and limit alcohol intake.
  • Consume a diet rich in fresh fruits and vegetables.
  • If you have symptoms of an ulcer or have been diagnosed with H. Pylori infection, you should see a doctor for treatment of the symptoms and eradication of the infection.

Source: Health Promotion Board, Singapore
www.hpb.com.sg

Sunday, 6 May 2012

Liver Cancer - HPB Singapore


Liver cancer is the fourth common cancer among males in Singapore (NRDO cancer registry 2006).
When the cancer occurs in the cells of the liver it is called primary liver cancer. When cancer from other organs such as colon, lung and breast spreads to liver it is called metastatic liver cancer.



Types of primary liver cancer


Primary liver cancer is classified based on the type of cells affected by cancer:

  • Hepatocellular carcinoma starts in the liver cells which are called hepatocytes.
  • Cholangiocarcinoma or bile duct cancer begins in the bile ducts.
  • Hepatoblastoma is a rare type of liver cancer affecting young children.
  • Hemangiosarcoma is a rare cancer arising from the blood vessels of the liver.

Metastatic liver cancer is more common than primary liver cancer and spreads to the liver from:

  • Stomach
  • Intestine
  • Breast
  • Pancreas
  • Lung
  • Uterus

Risk factors


  • Chronic hepatitis (long standing liver infection) can be caused By Hepatitis B virus and Hepatitis C virus.
  • Liver Cirrhosis is a condition in which the normal liver cells are damaged and replaced with scar tissue.
  • Exposure to Aflatoxin which is produced by a mould found on peanuts and other nuts, corn and grains.
  • Diabetes
  • Males are twice likely to get liver cancer than women.
  • Family history of liver cancer.
  • Bile duct disease called primary sclerosing cholangitis.

Signs & symptoms


In early stages of liver cancer, most patients may not have any specific symptoms. When symptoms appear, they may include some or all of the following:

  • Loss of appetite and weight
  • Abdominal pain on the right side of your tummy which may extend to your back and shoulder
  • Nausea and vomiting
  • General weakness and fatigue
  • Abdominal swelling with a mass or fluid (ascites)
  • Yellowish discoloration of the skin and whites of your eyes (jaundice)

Diagnosis


These include:

  • Ultrasound (Scan).
  • Liver Biopsy is procedure where a small sample of tissue is taken to be examined under the microscope.
  • CT (computerised tomography) and MRI (magnetic resonance imaging).
  • Blood tests for the presence of a cancer marker called alpha-fetoprotein (AFP).

Treatment


Treatments for primary liver cancer include:

  • Surgical resection of the tumour if the cancer is confined to a localised area and in some cases the tumour can be removed completely.
  • Alcohol (Ethanol) injection involves injecting ethanol directly to the tumors through the skin under scan guidance to kill cancer cells.
  • Radiofrequency ablation involves the use of electric current in the electromagnetic range to destroy cancer cells.
  • Cryoablation involves the application of extreme cold through a metallic probe under ultrasound scan guidance.
  • Liver transplantation involves removal of the diseased liver and replacement with a healthy, donor liver.
  • Radiation therapy involves the use of high power energy beams to destroy cancer cells or shrink tumours and can be used for localised tumours.
  • Chemotherapy involves the use of cancer drugs to kill cancer cells.

Recurrent Cancer


Recurrent cancer means that the cancer has resurfaced after the initial treatment. Most cancers recur within two years of treatment. The treatment may radiotherapy, chemotherapy or combination of both.

Coping with liver cancer


It can be challenging to live with a life threatening condition such as liver cancer. As it is often diagnosed at an advanced stage, it can have a devastating affect on your mind. Some tips include:

  • Learning all about your illness from credible resources such as books and reliable sites on the internet.
  • Involving close family members and friends to combat the pain and anxiety associated with advanced stages of cancer.
  • Staying active and taking time to relax. It is important to eat well and get enough rest to fight fatigue and stress of cancer.
  • Coming to terms with your disease and discussing issues which are important to you such as hospice care with your family and medical team.
  • Seeking the services of an oncology counsellor or religious counsellor to discuss end-of-life issues or ethical issues which are important to you.

Prevention


You can reduce the risk of developing liver cancer by protecting yourself from hepatitis infection and cirrhosis which are leading causes of liver cancer.

  • Take action! Get vaccinated with Hepatitis B vaccine to reduce the risk of Hepatitis B infection which is effective in both adults and children.
  • Take measures to prevent Hepatitis C which include:
    1. Learning more and educating others about viral hepatitis and the way it spreads from person to person.
    2. Not engaging in unprotected sex.
    3. Avoiding body piercing and tattooing as needles if not sterilised properly can spread the virus.
    4. Not abusing drugs and sharing intravenous drug needles.
    5. Avoiding alcohol abuse and addiction.
    6. Being cautious about receiving blood or blood products.

Source: Health Promotion Board, Singapore
www.hpb.gov.sg

Tuesday, 4 October 2011

Ovarian Cancer - Singapore Health Promotion

Ovarian cancer is the fifth most common cancer in among Singaporean women.

Symptoms of ovarian cancer in the early stages are often non-specific and mimic those of many digestive and bladder disorders.



Women have two ovaries, one on each side of the womb each about the size of an almond which produce eggs (ova) as well as the female sex hormones oestrogen and progesterone.

Ovarian cancer is a disease in which normal ovarian cells begin to grow in an uncontrolled, abnormal manner and produce tumours in one or both ovaries.

Types of ovarian cancer


Three basic types of ovarian tumours include:

  • Epithelial tumours. About 85 percent to 90 percent of ovarian cancers.
  • Germ cell tumours. These tumours occur in the egg-producing cells of the ovary and generally occur in younger women.
  • Stromal tumours. These tumours develop in the oestrogen- and progesterone-producing tissue that holds the ovary together.

Causes


The causes of ovarian cancer remain unknown. It is believed to be multi-factorial which includes genetic and environmental factors.

Risk factors


Factors which may increase the risk of ovarian cancer include:

  • Inherited gene mutations.
    • The most significant risk factor for ovarian cancer is having an inherited mutation in genes called breast cancer gene 1 (BRCA1) and breast cancer gene 2 (BRCA2) which are responsible for about 5 percent to 10 percent of ovarian cancers.
    • Another inherited syndrome called hereditary non-polyposis colorectal cancer (HNPCC) is associated with increased risk of cancers of the uterine lining (endometrium), colon, ovary, stomach and small intestine.
  • Family history. If you there is one first-degree relative (a mother, daughter or sister) with ovarian cancer the risk of developing cancer is 5 percent.
  • Age. Ovarian cancer most often develops after menopause.
  • Childbearing status. Women who have had at least one pregnancy and the use of oral contraceptives appear to offer some protection against ovarian cancer.
  • Infertility increases the risk of ovarian cancer even without use of fertility drugs.
  • Hormone replacement therapy (HRT) use for five or more years has been shown to significantly increase the risk of ovarian cancer.
  • Obesity in early adulthood. Women who are obese at age 18 are at increased risk of developing ovarian cancer before menopause.

Symptoms


Women with ovarian cancer are more likely to consistently experience the following symptoms:

  • Abdominal pressure, fullness, swelling or bloating
  • Urinary urgency
  • Pelvic discomfort or pain

Additional signs and symptoms may include:

  • Persistent indigestion, gas or nausea
  • Changes in bladder habits, including a frequent need to urinate
  • Loss of appetite or unexplained weight loss
  • Pain during intercourse (dyspareunia)
  • Low back pain

Diagnosis


  • Pelvic examination includes examination of the vagina, uterus, rectum and pelvis.
  • Ultrasound uses high-frequency sound waves to produce images of the inside of the body to evaluate the size, shape and configuration of the ovaries.
  • CA 125 blood test. CA 125 is a protein and many women with ovarian cancer have abnormally high levels of CA 125 in their blood. However, a number of noncancerous conditions also cause elevated CA 125 levels.
  • Imaging tests may include computerized tomography (CT) and magnetic resonance imaging (MRI) and a chest X-ray to determine if cancer has spread to the lungs or to the pleural space surrounding the lungs.

Treatment


Treatment of ovarian cancer usually involves a combination of surgery and chemotherapy.

Surgery


Women with ovarian cancer often require a more extensive operation that includes removing ovaries, fallopian tubes, and the uterus as well as nearby lymph nodes and a fold of fatty abdominal tissue known as the omentum.

Chemotherapy


Chemotherapy involves the use of drugs designed to kill any remaining cancer cells after surgery.

Side effects include:

  • abdominal pain
  • nausea ,vomiting and
  • infection.

Screening


Tests that may detect (find) ovarian cancer that are being studied include:

  • Pelvic exam
  • Transvaginal ultrasound
  • CA-125 assay

Currently, there is no standard or routine screening test for ovarian cancer.

There is insufficient evidence to recommend for or against the screening of asymptomatic women at high risk of developing ovarian cancer.

Prevention


Some of the risk factors for developing ovarian cancer are modifiable, though some cannot be avoided. These include:

  • Obesity: Excess body fat increases the risk of ovarian cancer. Diet, nutrition and physical activity during the teen years may play a role in prevention.
  • Women at high risk of developing ovarian cancer such as those with strong family history or women carrying BRCA1 or BRCA2 mutation should consider having a cancer risk assessment by their health professional and advice on options available to reduce the risk of ovarian cancer.

http://www.hpb.gov.sg/diseases/article.aspx?id=596

Wednesday, 7 September 2011

Lung Cancer - Singapore Health Promotion Board


Source: Health Promotion Board, Singapore

Lung cancer is the 2nd most common cancer in males and 3rd most common cancer in females in Singapore.

Lung cancer can be prevented. By avoiding smoking or quitting smoking, the risk of developing lung cancer can be reduced.

Protection from other risk factors such as exposure to asbestos and secondhand smoke also decreases the risk the lung cancer.

The commonly used screening tests for early detection of lung cancer include chest X-ray and Sputum Cytology.



Types of Lung Cancer


The two general types of lung cancer include:

  • Small cell lung cancer also called oat cell carcinoma occurs almost exclusively in heavy smokers and is less common than non-small cell lung cancer.
  • Non-small cell lung cancers include squamous cell carcinoma, adenocarcinoma and large cell carcinoma.

Risk factors


Risk factors for lung cancer include:

  • Smoking. The risk of lung cancer increases with the number of cigarettes a person smokes each day and the number of years one has smoked. Quitting at any age can significantly lower the risk of developing lung cancer.
  • Sex. Current or former women smokers have a greater risk of lung cancer than do men who have smoked an equal amount.
  • Exposure to secondhand smoke. Even if a person does not smoke, the risk of lung cancer increases if there is exposure to secondhand smoke.
  • Exposure to asbestos and other chemicals such as arsenic, chromium, nickel and tar soot at the work place can increase the risk of developing lung cancer, especially in smokers.
  • Family history of lung cancer.

Symptoms


Lung cancer may not produce any symptoms in its early stages.

Signs and symptoms of lung cancer typically occur in advanced disease and these include:

  • Persistent cough
  • Coughing up blood
  • Shortness of breath
  • Chest pain
  • Wheezing
  • Hoarseness

Diagnosis


The following tests may be used to diagnose lung cancer:

  • Imaging tests such as X-ray or a CT scan of the lungs may reveal an abnormal mass or nodule.
  • Sputum cytology involves examining the sputum (phlegm) under the microscope which can sometimes reveal the presence of lung cancer cells.
  • Biopsy involves taking a sample of abnormal cells removed in a procedure called a biopsy.

Treatment


Treatment options typically include:

  • Surgery involves removal of the lung cancer and a margin of healthy tissue.
  • Chemotherapy uses drugs to kill cancer cells with one or more chemotherapy drugs.
  • Radiation therapy uses high-powered energy beams such as X-rays to kill cancer cells.

Lung cancer screening


Two tests have commonly been used to screen for lung cancer.

  • Chest X-ray
  • Sputum cytology

Chest X-ray


A chest x-ray is an x-ray of the organs and bones inside the chest making a picture of lungs and other organs in the chest.

Sputum cytology


Sputum cytology is a procedure in which a sample of sputum (mucus that is brought up from the lungs by coughing) is viewed under a microscope to check for cancer cells.

Prevention


Currently there are agents that have proven to be effective for preventing lung cancer. However several clinician based and community-based interventions show that the risk of lung cancer can be reduced by:

  • Avoiding smoking.
  • Quitting smoking. Quitting reduces the risk of lung cancer, even if one has smoked for years. Options include nicotine replacement products, medications and support groups.
  • Avoiding passive smoking. Encourage your partner/spouse or colleague who smokes to quit smoking and request him or her to smoke outside the home or work premises. Choose smoke-free zones and avoid crowded places such as bars and restaurants.
  • Avoiding exposure to toxic chemicals at workplace by taking precautions such as wearing a face mask to prevent exposure to toxic chemicals at the workplace.
  • Eating a diet full of fruits and vegetables, drinking alcohol in moderation and exercising regularly.

Source: Health Promotion Board, Singapore
www.hpb.gov.sg

Prostate Cancer - Singapore Health Promotion Board


Source: Health Promotion Board, Singapore

Prostate cancer is the 3rd most common cancer among Singaporean men.

Prostate specific tumor antigen (PSA) blood testing can be done in men with symptoms suggestive of prostate cancer or in men at high risk of developing prostate cancer.



Prostate cancer is cancer of the small walnut-shaped gland in males that produces seminal fluid, the fluid that nourishes and transports sperm.

Prostate cancer is the 3rd most common cancer among men in Singapore.

Causes


The cause prostate cancer is not clear.

A combination of factors may play a role in prostate cancer such as family history, ethnicity, hormones, diet and the environment.

Risk factors


The main risk factors include:

  • Age. The risk of prostate cancer increases after the age of 50 years.
  • Race or ethnicity. Dark skinned men have a higher risk of developing and dying of prostate cancer.
  • Family history of prostate cancer increases the risk of prostate cancer.
  • Diet. A high-fat diet and obesity may increase your risk of prostate cancer.
  • High testosterone levels in men who use testosterone therapy.

Symptoms


In the early stages of prostate cancer, there may be no symptoms.

In the later stages, symptoms of prostate cancer may include urinary symptoms such as:

  • Difficulty passing urine or slowing of the flow of urine to a trickle
  • Decreased force in the stream of urine
  • Blood in your urine or semen

Advanced prostate cancer which has spread to:

  • Bones may cause bone pain, fractures and compression of the spine.
  • Lymph nodes may cause swelling of the leg or discomfort.

Diagnosis


These include:

  • Digital rectal examination (DRE) to detect any abnormalities in the texture, shape or size of the prostate gland.
  • Prostate-specific antigen (PSA) test involves taking a blood sample from a vein and testing for PSA, a substance that is naturally produced by the prostate gland to help liquefy semen. High levels will warrant further investigation.
  • Tran rectal ultrasound to detect any abnormalities in the prostate gland.
  • Prostate biopsy involves taking thin sections of tissue from the prostate gland.

Additional tests include:

  • Bone scan
  • Ultrasound
  • Computerized tomography (CT) scan
  • Magnetic resonance imaging (MRI)
  • Lymph node biopsy

Complications


The typical complications of prostate cancer and its treatments include:

  • Spread of cancer to nearby organs or travel through the bloodstream or lymphatic system affecting the bones or other organs.
  • Pain when the cancer spreads to bones it can cause excruciating pain.
  • Difficulty urinating (urinary incontinence).
  • Erectile dysfunction (ED) or impotence.
  • Depression after a diagnosis of prostate cancer or after trying to cope with the side effects of treatment.

Treatment


The most common treatments for prostate cancer include the following:

External beam radiation therapy


External beam radiation treatment uses high-powered X-rays to kill cancer cells.

Radioactive seed implants


Radioactive implants, also known as brachytherapy, deliver a higher dose of radiation than do external beams.

Hormone therapy


Hormone therapy involves using drugs to stop the body from producing the male sex hormones testosterone, which can stimulate the growth of cancer cells.

Radical prostatectomy


Surgical removal of prostate gland is used to treat cancer that is confined to the prostate gland.

Chemotherapy


This type of treatment uses drugs to destroy rapidly growing cancer cells.

Prevention


Prostate cancer cannot be prevented.

However certain measures are known to reduce the risk of developing prostate cancer.

  • Eating fruit and vegetables and avoiding high fat diet. High-fat diets have been linked to prostate cancer.
  • Foods rich in antioxidants such as lycopene include raw or cooked tomatoes, tomato products, grapefruit and watermelon help to fight cancer. Garlic and other vegetables such as broccoli, Brussels sprouts, cabbage and cauliflower also help fight cancer.
  • Get regular exercise. Men who are physically active usually have less-severe symptoms than do men who get little exercise.
  • Non-steroidal anti-inflammatory drugs (NSAIDs) might prevent prostate cancer. These drugs include ibuprofen and naproxen.

Source: Health Promotion Board, Singapore
www.hpb.gov.sg

Colorectal cancer - Singapore Health Promotion Board


Source: Health Promotion Board, Singapore


Colorectal Cancer - Anatomy (image)

Colorectal cancer is the number 1 cancer in Singapore.

Screening tests such the faecal immunochemical test (FIT) and screening colonoscopy can help prevent colorectal cancer.



Colorectal cancer is cancer of the large intestine (colon and rectum). Most cases of colorectal cancer begin as small, non-cancerous growths attached to the wall of the colon. These growths are called polyps and may become cancerous over time.

Colorectal Cancer - Colon Polyp (image)

Symptoms


In the early stages, people with colorectal cancer may not experience any symptoms.

In the later stages, the common signs and symptoms include:

  • A change in the bowel habits, including diarrhoea or constipation
  • Presence of blood in the stool
  • Persistent abdominal discomfort such as cramps, gas or pain

Screening


Screening for colorectal cancer should begin from age 50 for people with no symptoms. The recommended screening tests are:


CC_FIT (image)

The FIT is a test that

  • detects the presence of small amounts of blood (that can’t be seen with the naked eye) in the stools.
  • is safe, quick and easy to do, and can be done at home, without the need to change your diet before the test.
  • should be done once a year

You will be given 2 FIT kits. Two stool samples should be collected over two days for a more accurate result.

Screening using FIT should be done once a year. However, if you develop signs or symptoms even after a normal FIT result, please see your doctor immediately.


Colonoscopy (image)

The screening colonoscopy

  • uses a flexible tube (colonoscope) to look at the inner lining of the large intestine (colon and rectum).
  • takes about 20 – 30 minutes to complete
  • has to be done in a hospital by a doctor trained in doing colonoscopies
  • should be done once every 10 years

Discuss with your doctor which screening test is best for you.

Treatment


The three main treatment options for colorectal cancer are: surgery, chemotherapy and radiation which may be used alone or in combination.

Surgical options:

  • Surgery involves removal of the part of the colon that contains the cancer.
  • Chemotherapy

    Chemotherapy can be used to destroy cancer cells after surgery, to control tumour growth or to relieve symptoms of colorectal cancer. Possible side effects of chemotherapy include:
    • Nausea and vomiting
    • Mouth sores
    • Fatigue
    • Hair loss and diarrhoea
  • Radiation therapy

    Radiation therapy uses X-rays to kill any cancer cells that might remain after surgery, to shrink large tumours before an operation so that they can be removed more easily, or to relieve symptoms of colorectal cancer. Side effects of radiation therapy may include:
    • Diarrhea
    • Rectal bleeding
    • Fatigue

Interview with a Colorectal Cancer Survivor.


For more videos on colorectal cancer, please visit www.youtube.com/hpbsg

Prevention


You can take steps to reduce your risk of colorectal cancer by:


Source: Health Promotion Board, Singapore

For Different types of cancer, see: http://www.hpb.gov.sg/cancer/default.aspx

Dietary Guidelines For Singaporeans - 2003

Source: Health Promotion Board, Singapore

The Dietary Guidelines for Adult Singaporeans was updated in 2003. The guidelines were first developed in 1988 and revised in 1993, and the latest revision was in 2003. The guidelines are intended for healthy adult Singaporeans between the age of 18 to 65 years and are meant to be applied to the total diet. They are not appropriate for assessing individual food items. Similarly, the guidelines are designed to be used as a complete set and individual guidelines should not be used in isolation.

1. Eat a Variety of Foods using the Healthy Diet Pyramid as a Guide.
No single food can supply all the nutrients in the amounts an individual needs each day. To get all the nutrients and other substances needed for optimal health, use the Healthy Diet Pyramid to guide food choices.

2. Achieve and Maintain Body Weight Within the Normal Range.
Use BMI and Waist Circumference to evaluate the normal range. Individual who need to lose weight have to make changes to their eating habits and amount of physical activity. A gradual weight loss is encouraged in overweight and obese individuals.

3. Eat Sufficient Amounts of Grains, especially Whole Grains.
Eat more grains which is the Rice and Alternatives Group in the Healthy Diet Pyramid. Grains provide carbohydrate (starch), dietary fibre, vitamins, minerals and phytochemicals that are important for good health. Whole grains are unpolished grains containing bran and germ, such as rolled oats, brown rice, whole flour and bread.

4. Eat More Fruit and Vegetables Every Day
Scientific studies show that a diet rich in fruit and vegetables can lower the risk of developing heart disease, stroke, and certain types of cancer by 20-30%. Vegetables and most fruit are fat-free, and they provide essential vitamins, minerals, phytochemicals (such as flavanoids and caretenoids) and dietary fibre (both soluble and insoluble fibres). thereby increasing vitamin A, vitamin C and fibre intakes.

5. Choose and Prepare Food with Less Fat, especially Saturated Fat
Dietary fat provides energy, contains essential fatty acids and acts as a carrier for fat- soluble vitamins A, D, E and K. We need some fat in the food we eat. However, fat is a concentrated source of energy - a diet high in fat can provide excess calories and lead to overweight and obesity. Aim for a diet low in saturated fat and high in unsaturated fats to reduce the risk of coronary heart disease and stroke.

6. Choose and Prepare Food with Less Salt and Sauces.
Table salt contains 40% sodium. Excessive sodium intake can affect blood pressure for people that are sensitive to it. Reduce intake of salt-preserved, cured and smoked foods to help reduce your cancer risk and reduce salt intake.

7. Choose Beverages and Food with Less Sugar.
Added sugar in beverages and food provide empty calories with little nutritional value. Excess energy intake beyond daily requirements can lead to weight gain and obesity. Frequently consuming sweet foods between meals can lead to dental decay, if oral hygiene is neglected.

8. If You Drink Alcoholic Beverages, Do So in Moderation.
Alcoholic beverages supply calories, but provide little or no nutrients. Drinking alcohol excessively is also the cause of health problems such as liver and pancreas damage, hypertension and certain cancers. Excessive alcohol consumption also alters judgement and may cause motor and industrial accidents, as well as social and psychological problems. It can also lead to dependency and addiction.

Source:
Dietary Guidelines 2003: For Adult Singaporeans (18 - 65 years) - Health Promotion Board, Singapore


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Food-based Dietry Guidelines for Adults

Dietary guidelines are crucial in helping people to adopt healthier food consumption habits. In Singapore, the dietary guidelines were first developed in 1990, and revised in 1993. A new set was then released in 2003, which reflected a shift from nutrient-based to food-based recommendations. This was in line with the increasing recognition that food provide not only nutrients, but also other non-nutrient compounds (e.g. phytochemicals such as lycopene, isoflavones, lutein) which appear to be protective against chronic diseases.

The 2003 dietary guidelines are currently being revised. The evidence reviewed will be graded according to the Scottish Intercollegiate Guidelines Network (SIGN) system of grading evidence, which is also used by the Clinical Practice Guidelines (CPG) working groups in Singapore.

The 8 Dietary Guidelines for Adult Singaporeans (18 to 69 years) are as follow:

Enjoy a variety of food using the Healthy Diet Pyramid as a guide


People who have a varied diet, i.e. those who eat from all four food groups and have different types of food from each food group, are more likely to meet their nutrient requirements. The food items chosen should be low in fat, especially saturated fat; low in salt and added sugar. Read about the Healthy Diet Pyramid and its recommendations.

An area of focus under this guideline is on calcium intake. Calcium is vital for maintaining bone health and reducing the risk of osteoporosis. For adolescents and adults up to the age of 30 years, an adequate intake of calcium is one of several factors that have been associated with maximal accumulation of bone mass. Individuals attain their peak (maximal) bone mass before the age of 30 years, after which bone mass gradually declines; though continued consumption of calcium-rich foods can help prevent bone loss.

Milk and dairy products are the best sources of calcium. Other good sources include dark green leafy vegetables (e.g. kai lan, chye sim), fish with edible bones, calcium-fortified products (e.g. calcium-fortified soybean milk and cereals) and tofu (which is set with calcium).

Achieve and maintain body weight within the normal range


Body weight maintenance is achieved by balancing energy intake (e.g. in the form of calories from food) and energy output (e.g. physical activity). When more energy is consumed than expended, weight gain occurs. If a person consistently consumes more energy than they expend over a period of time, they are at risk of being overweight or obese.

A person’s Body Mass Index (BMI) can be used to assess their risk of developing chronic diseases. BMI uses the height and weight of an individual to estimate his or her total body fat. Singaporeans have been found to at risk of developing cardiovascular disease and diabetes at BMI values of 23 kg/m2 and above.

BMI (kg/m2) (for adults) Risk of heart disease, etc
27.5 and above High risk
23.0-27.4 Moderate risk
18.5-22.9 Low risk (healthy range)
<18.5 Risk of nutritional deficiency diseases and osteoporosis

Eat sufficient amount of grains, especially whole grains


At least one serving of rice & alternatives should come from wholegrain food as they contain both the bran (which is high in B-vitamins) and germ (which is rich in Vitamin E & phytochemicals). Refined grains only contain the endosperm (the bran and germ is removed during the milling process) and do not contain as many nutrients or fibre compared to wholegrain foods. Examples of wholegrain food include oats, brown rice and wholemeal/whole wheat versions of noodles, bread and breakfast cereals.
Whole Grains
People who have a diet rich in whole-grains have a lower risk of cardiovascular diseases and Type 2 Diabetes. There is also evidence to suggest that people whose diet is rich in whole-grains have a reduced risk of colorectal and oesophageal cancers. Including whole-grain foods in your diet may assist in weight loss too, although more studies are needed to confirm these findings.

Eat more fruit and vegetables every day


Individuals should aim to eat at least 2 servings of fruit and 2 servings of vegetables every day.

For vegetables, this includes all vegetables fresh, frozen and well-drained canned vegetables, except tubers (e.g. potatoes, yam) and legumes (e.g. beans, lentils). Tubers belong to the Rice & Alternatives food group due to its high starch content, and legumes belong to the Meat & Alternatives food group as they are good sources of protein. For fruit, this includes fresh, frozen, well-drained canned or dried fruit or pure (100%) fruit juice with no added sugar.

A diet rich in fruit and vegetables is associated with a reduced risk of coronary heart disease and stroke. Fruit and vegetables may also protect against cancers of the mouth, pharynx, larynx, esophagus, stomach and lung (fruit only). In addition, fruit and vegetables may be a useful component of programmes designed to achieve and sustain weight loss.

Choose and prepare food with less fat, especially saturated fat


Fat is needed for certain metabolic functions in the body. However, it is also a concentrated source of energy and a diet high in fat can provide excess calories, increasing the risk of overweight and obesity.

Total fat should be limited to 25-30% of total calorie intake, of which less than 10% is from saturated fat. The balance should come from mono- and polyunsaturated fats. Sources of saturated fat include fatty cuts of meat, high-fat dairy products, food made with coconut milk and also food prepared with palm-based vegetable oil. A high intake of saturated fat is linked to an increased risk of cardiovascular diseases.

In addition, there is limited, but suggestive evidence that total fat intake is associated with cancer of the lung and the breast (postmenopausal women only).

Choose and prepare food with less salt and sauces


Salt is one of the main sources of sodium in the diet. The average intake of salt of an average adult in Singapore is 9g per day, which is more than the recommended 5g per day. Studies continue to show that blood pressure can be lowered when intake of salt is reduced to less than 5g per day. Other sources of sodium include sauces, monosodium glutamate (MSG), preservatives and salt substitutes. There is good evidence to show that reducing sodium intake from salt and other sources is able to lower blood pressure in both healthy individuals and individuals with high blood pressure.

An excessive consumption of salt-preserved, cured or smoked food has also been associated with higher risk of stomach and nasopharyngeal cancers. The higher risk is attributed to salt and sodium nitrates commonly used as preservatives in these products.

Choose beverages and food with less sugar


Beverages and food with added sugar usually provide empty calories. Added sugar refers to sugar that is added to food or drinks during manufacturing, cooking or at the table. Excessive consumption of beverages and food high in added sugar can contribute considerably to energy intake and may lead to weight gain if the excess calories are not expended. In addition, these items may displace other more nutritious food in the diet.

Added sugar should contribute to no more than 10% of dietary energy. This translates to approximately 40 – 55g (8-11 tsp) daily. This limit includes sugar added to beverages as well as food such as cakes and candies.

If you drink alcoholic beverages, do so in moderation


Individuals who choose to drink should have no more than 2 standard drinks a day for a woman, and no more than 3 drinks a day for a man. One standard drink contains 10g of pure alcohol and is equivalent to can of beer (220ml), 1 glass of wine (100ml), or 1 nip (30ml) of spirits. People who consume more than the recommended amounts should gradually cut down on their intake.

Studies show that drinking in moderation may protect against heart disease in middle-aged men. But due to the harmful health and social consequences of excessive alcohol consumption, adults who do not drink alcoholic beverages should not be encouraged to start.


Source: Health Promotion Board, Singapore