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Saturday, 5 December 2020

UK approves Pfizer-BioNTech Covid-19 vaccine in world first, says no ‘corners cut’

 Britain to start vaccinating people against Covid-19 next week, with PM Boris Johnson saying it will ‘allow us to reclaim our lives’

  • England leaves month-long lockdown but sees new virus curbs
The UK had signalled it would move swiftly in approving a vaccine as part of an operation to protect its population. Photo: AFP
The UK had signalled it would move swiftly in approving a vaccine as part of an operation to protect its population. Photo: AFP

Britain on Wednesday became the first Western country to approve a
Covid-19 vaccine for general use, announcing a roll-out of Pfizer-BioNTech’s drug from next week in a historic advance for humanity’s fightback against the coronavirus.

“It’s the protection of vaccines that will ultimately allow us to reclaim our lives and get the economy moving again,” Prime Minister
Boris Johnson said after the approval by the UK’s independent medicines regulator.


But he urged the public to remain cautious on the day that England exited a four-week lockdown and reimposed regional curbs.


Health Secretary Matt Hancock said that starting with care home residents and health and care staff, Britain’s National Health Service will begin with 800,000 doses “early next week” and ramp up to “millions” of inoculations by the end of the year.


“Help is on its way,” he told BBC radio. “We can see the dawn in the distance but we have to get through to the morning,” Hancock added, underscoring the appeal for the public to continue adhering to social restrictions.


“The UK is the first country in the world to have a clinically approved vaccine for supply,” he tweeted earlier.

England’s chief medical officer, Chris Whitty, also welcomed the “excellent news” but stressed: “It will take until spring until the vulnerable population who wish to are fully vaccinated. We can’t lower our guard yet.”

Britain’s Medicines and Healthcare products Regulatory Agency (MHRA) said it took no short cuts in its recommendation to approve the vaccine, and it had used overlapping trials and “rolling reviews” since June to reach the determination in record time.

“That doesn’t mean any corners have been cut – none at all,” said June Raine, its chief executive. “The safety of the public will always come first.”

“If you climb a mountain, you prepare and prepare,” she said. “On 10th November we were at base camp. When we got the final analysis we were ready for that last sprint that takes us to today.”

The breakthrough will encourage hopes the world can finally get back on course in 2021 after a year of traumatic losses, both human and economic.

The novel coronavirus has killed nearly 1.5 million people since it was first detected in China 12 months ago. At least 63 million cases have been registered.

Other vaccines expected to come on stream soon include ones from Moderna and AstraZeneca/Oxford University.

The United States and Europe on Tuesday fleshed out plans to administer Covid-19 vaccines as soon as they gain approval, with a US panel recommending that health care workers and nursing home residents be given top priority.

In the United States, an advisory panel of the Centres for Disease Control and Prevention proposed that health care workers and nursing home residents – 24 million people in total – be the first in line for Covid jabs.

Those two groups have accounted for about 40 per cent of deaths thus far in the US, which has the world’s highest coronavirus toll. Britain has the highest toll in Europe.

The European Medicines Agency said it would hold an extraordinary meeting on December 29 “at the latest” to consider emergency approval for the vaccine developed by Germany’s BioNTech and US giant Pfizer.

After months of “rigorous” clinical trials and thorough analysis of the Pfizer-BioNTech data, the MHRA “concluded that the vaccine has met its strict standards of safety, quality and effectiveness”, the UK health ministry said in a statement.



“To aid the success of the vaccination programme it is vital everyone continues to play their part and abide by the necessary restrictions in their area so we can further suppress the virus and allow the NHS to do its work without being overwhelmed.”



Pfizer chairman Albert Bourla said it was a “historic moment in the fight against Covid-19”.


“This authorisation is a goal we have been working toward since we first declared that science will win, and we applaud the MHRA for their ability to conduct a careful assessment and take timely action to help protect the people of the UK,” he said.


Pfizer and BioNTech added that they expected further regulatory decisions from other countries “in the coming days and weeks”.
65,242,091
Confirmed Covid-19 cases
1,506,699
total deaths
41,962,730
total recovered
 
Cases
Deaths
United States
14,147,241
276,383
India
9,571,559
139,188
Brazil
6,487,084
175,270
Russia
2,382,012
41,730
France
2,310,271
54,231
United Kingdom
1,678,419
60,210
Spain
1,675,902
46,038
Italy
1,664,829
58,038
Argentina
1,447,732
39,305
Colombia
1,343,322
37,305
Mexico
1,144,643
108,173
Germany
1,137,721
18,097
Poland
1,028,610
18,828
Iran
1,003,494
49,348
Peru
967,075
36,076
South Africa
800,872
21,803
Ukraine
793,372
13,394
Turkey
733,261
14,316
Belgium
584,857
17,033
Iraq
558,767
12,361
Chile
555,406
15,519
Indonesia
549,508
17,199
Netherlands
546,982
9,645
Czechia
537,663
8,641
Romania
492,211
11,876
Bangladesh
471,739
6,748
Philippines
435,413
8,446
Pakistan
410,072
8,260
Canada
399,770
12,423
Morocco
368,624
6,063
Saudi Arabia
358,102
5,930
Israel
341,042
2,891
Switzerland
340,115
5,181
Portugal
307,618
4,724
Austria
293,430
3,538
Sweden
272,643
7,007
Nepal
237,589
1,551
Hungary
231,844
5,324
Jordan
231,237
2,909
Serbia
199,158
1,765
Ecuador
195,884
13,612
Kazakhstan
177,386
2,438
United Arab Emirates
172,751
585
Panama
171,219
3,141
Japan
155,938
2,174
Bulgaria
155,193
4,503
Georgia
147,636
1,387
Dominican Republic
146,009
2,335
Bolivia
145,186
8,982
Kuwait
143,574
884
Costa Rica
142,505
1,757
Belarus
141,609
1,181
Qatar
139,477
239
Croatia
139,415
1,964
Armenia
138,508
2,254
Azerbaijan
133,733
1,510
Lebanon
132,817
1,067
Oman
124,329
1,435
Guatemala
124,053
4,209
Egypt
117,156
6,713
Moldova
112,307
2,363
Ethiopia
111,579
1,724
Greece
111,537
2,706
Slovakia
111,208
930
Honduras
109,760
2,938
Venezuela
103,548
909
Tunisia
99,280
3,359
Burma
95,018
2,028
West Bank and Gaza
92,708
780
Bosnia and Herzegovina
91,539
2,812
Bahrain
87,432
341
Mainland China
86,542
4,634
Kenya
86,383
1,500
Algeria
85,927
2,480
Denmark
85,663
858
Paraguay
85,477
1,796
Libya
84,849
1,212
Slovenia
81,349
1,592
Kyrgyzstan
73,933
1,285
Uzbekistan
73,431
611
Ireland
73,228
2,080
Nigeria
68,303
1,179
Malaysia
68,020
365
Lithuania
67,066
564
North Macedonia
65,231
1,847
Singapore
58,230
29
Ghana
51,667
323
Afghanistan
46,718
1,841
Albania
40,501
852
Kosovo
40,117
1,026
El Salvador
39,130
1,134
Norway
37,371
353
Montenegro
36,932
516
Luxembourg
36,429
339
Korea, South
36,332
536
Australia
27,949
908
Finland
26,422
408
Sri Lanka
26,038
129
Cameroon
24,487
441
Uganda
21,612
206
Cote d'Ivoire
21,389
132
Latvia
19,307
235
Sudan
18,535
1,271
Zambia
17,730
357
Madagascar
17,513
255
Senegal
16,217
335
Mozambique
15,918
132
Angola
15,361
352
Namibia
14,599
151
Estonia
13,469
123
Guinea
13,167
76
Congo (Kinshasa)
13,132
337
Maldives
13,106
47
Tajikistan
12,308
87
Botswana
11,531
34
Cyprus
11,523
54
Cabo Verde
10,938
107
Jamaica
10,911
259
Zimbabwe
10,424
280
Malta
10,197
148
Haiti
9,331
233
Gabon
9,239
60
Mauritania
9,005
181
Cuba
8,531
136
Syria
8,147
432
Bahamas
7,549
163
Belize
7,236
164
Andorra
6,904
77
Trinidad and Tobago
6,725
121
Hong Kong
6,701
111
Eswatini
6,474
122
Uruguay
6,455
80
Malawi
6,043
185
Rwanda
6,011
50
Nicaragua
5,838
161
Congo (Brazzaville)
5,774
94
Djibouti
5,689
61
Guyana
5,528
151
Iceland
5,448
27
Suriname
5,322
117
Equatorial Guinea
5,159
85
Central African Republic
4,918
63
Mali
4,880
162
Somalia
4,525
121
Thailand
4,053
60
Gambia
3,767
123
South Sudan
3,154
62
Burkina Faso
3,062
68
Benin
3,055
44
Togo
3,039
65
Guinea-Bissau
2,441
44
Sierra Leone
2,416
74
Yemen
2,239
624
Lesotho
2,145
44
New Zealand
2,069
25
San Marino
1,714
46
Chad
1,708
102
Liberia
1,663
83
Niger
1,640
76
Vietnam
1,361
35
Liechtenstein
1,339
17
Sao Tome and Principe
997
17
Mongolia
831
0
Diamond Princess
712
13
Burundi
692
1
Taiwan
685
7
Papua New Guinea
671
7
Monaco
630
3
Comoros
615
7
Eritrea
594
0
Tanzania
509
21
Mauritius
508
10
Bhutan
418
0
Cambodia
335
0
Barbados
281
7
Saint Lucia
262
2
Seychelles
183
0
Brunei
151
3
Antigua and Barbuda
144
4
Saint Vincent and the Grenadines
87
0
Dominica
85
0
Macau
46
0
Fiji
42
2
Grenada
41
0
Laos
39
0
Timor-Leste
31
0
Holy See
27
0
Saint Kitts and Nevis
22
0
Solomon Islands
17
0
Western Sahara
10
1
MS Zaandam
9
2
Marshall Islands
4
0
Vanuatu
1
0


The announcement came as England exited its month-long coronavirus lockdown, but most of the country remained under restrictions as a new regional system for cutting infection rates kicked in.


Johnson, a Covid-19 survivor, succeeded in winning a vote on the measures in parliament late Tuesday, despite significant opposition within his own Conservative ranks which underlined growing fatigue around the world with curbs.


“All we need to do now is to hold our nerve until these vaccines are indeed in our grasp and indeed being injected into our arms,” he told lawmakers before the vote.


Until then “we cannot afford to relax, especially during the cold months of winter”, he warned.


Russia was the first country to announce a successful vaccine candidate, the Sputnik V, and has begun a mass coronavirus vaccination campaign for its military. But the drug has not undergone Western clinical trials.


According to the World Health Organization, around 100 vaccine candidates are currently in development. Around a dozen of them are in the final phase three stage when the shot is tested on tens of thousands of volunteers.


Campaigners and governments have stepped up calls to ensure poorer countries enjoy equal access to successful vaccines.


https://www.scmp.com/news/world/europe/article/3112247/uk-approves-pfizer-biontech-covid-19-vaccine-world-first