PubMed PMC research articles on Graviola leaf extract

Graviola >Annona muricata< leaf extract  (also known as sour sop)

• Review Anticancer Properties of Graviola (<i>Annona muricata</i>): A Comprehensive Mechanistic Review.[Oxid Med Cell Longev. 2018]
• Review Potential Benefits of <i>Annona muricata</i> in Combating Cancer: A Review.[Malays J Med Sci. 2018]

Evaluation of cytotoxicity of aqueous extract of Graviola leaves on squamous cell carcinoma cell-25 cell lines by 3-

• Annona muricata leaves induced apoptosis in A549 cells through mitochondrial-med...
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• Possible mechanisms of action of the hypotensive effect of Annona muricata (soursop) in normotensive Sprague-Dawley rats.[Pharm Biol. 2012]
• Influence of different extraction conditions on antioxidant properties of soursop peel.[Acta Sci Pol Technol Aliment. 2016]
• New bioactive monotetrahydrofuran Annonaceous acetogenins, annomuricin C and muricatocin C, from the leaves of Annona muricata.[J Nat Prod. 1995]
• Antiproliferative activity and induction of apoptosis by Annona muricata (Annonaceae) extract on human cancer cells.[BMC Complement Altern Med. 2014]
• Review Annona muricata (Annonaceae): A Review of Its Traditional Uses, Isolated Acetogenins and Biological

• Emerging therapeutic potential of graviola and its constituents in cancers.[Carcinogenesis. 2018]
• Polyketide Natural Products, Acetogenins from Graviola (Annona muricata L), its Biochemical, Cytotoxic Activity and Various Analyses Through Computational and Bio-Programming Methods.[Curr Pharm Des. 2016]
• Antiproliferative activity of ionic liquid-graviola fruit extract against human breast cancer (MCF-7) cell lines using flow cytometry techniques.[J Ethnopharmacol. 2019]
• Synergistic interactions among flavonoids and acetogenins in Graviola (Annona muricata) leaves confer protection against prostate cancer.[Carcinogenesis. 2015]

• Annona muricata leaves induce G₁ cell cycle arrest and apoptosis through mitochondria-mediated pathway in human HCT-116 and HT-29 colon cancer cells.[J Ethnopharmacol. 2014]
• The chemopotential effect of Annona muricata leaves against azoxymethane-induced colonic aberrant crypt foci in rats and the apoptotic effect of Acetogenin Annomuricin E in HT-29 cells: a bioassay-guided approach.[PLoS One. 2015]

https://www.mskcc.org/cancer-care/integrative-medicine/herbs/graviola