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Friday, 5 May 2017

Chinese scientists use drop of blood to detect cancer

‍Scientists around the world are striving for effective detection of cancer in the early stages, and a Chinese scientist may have found a quick way of knowing whether malignant tumors exist in a patient's body, with just one drop of blood.
By Xie Zhenqi
2017-05-01 15:08 GMT+8
13km to Beijing
Luo Yongzhang and his team in Tsinghua University's School of Life 
Sciences in Beijing have successfully invented a reagent test kit of 
Hsp90α for clinical use, which can diagnose multiple kinds of cancer 
by analyzing a drop of human blood. 
Luo and his team members in a lab. / CCTV Photo
Malignant tumors in early phases can be cured but once they 
have spread all over the patient's body there is no way to save the 
person's 
life. 
However, it's extremely difficult to be aware of cancer in its early 
stages, as patients don't show obvious symptoms and thus it can 
only be found in its later stages, which is already too late, so to 
detect cancer early remains a global challenge for scientists. 
Scientists around the globe are working to find ways to detect cancer in its early stage. 
/ VCG Photo
Back in 1989, scientists have found a kind of heat shock proteins 
(HSP), named Hsp90α, which existed in human bodies and can 
be used as a cancer biomarker detection kit. 
Scientists around the globe have been working on it since then, 
and more than 10,000 journals have been published on accredited magazines, yet no one has actually turned their research results 
into medical products. 
However, Luo and his team seemed to have cracked the code, after 
working on the problem since 2009. The team has produced an 
artificial Hsp90α protein that gains structural stability by regrouping proteins. This means they are able to "create" the protein, in any 
quantity, and at any time ‍they wish to. 
The kit has since been used in clinical trials involving 2,347 patients 
at eight hospitals in China. It was the first clinical trial in the world 
to test if the protein could be a useful tumor biomarker for lung 
cancer, and it succeeded.
Now, the kit has been certified to enter the Chinese and European
 markets, 24 years after Hsp90α was discovered.
The final product that has been approved by government and ready to enter 
markets in China and Europe. / CCTV Photo
Cancer is a group of diseases involving abnormal cell growth with 
the potential to invade or spread to other parts of the body. 
In 2015, about 90.5 million people had cancer in the world, with 
roughly 14.1 million new cases occurring each year. Approximately 
8.8 million human deaths, or 15.7 percent of all deaths in the world, 
are caused by cancer. 
In China alone, 4.29 million people were detected as having cancer 
in 2015, and 2.8 million of them died in that year.