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Thursday 28 February 2013

Iron Overload Can Result in Poor Health

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by Carolyn Pierini, CLS (ASCP), CNC

Examining the body’s iron status through routine blood chemistry testing may uncover a silent killer especially in men. Iron overload (excess) may present without symptoms, disrupting the balance of inflammation especially in the liver and contributing to conditions such as liver cirrhosis, arthritis, dementia, stroke, vascular disease, and bronzing of the skin.

The protein transferrin is involved in the recycling and transport of iron in the blood. Calculating the percent of transferrin saturation can detect early iron overload and possibly save a life. Simply multiply the serum iron value by 100 and then divide the result by the TIBC (total iron binding capacity) value. With a result greater than 50 percent, iron overload or the more severe, hemochromatosis, should be ruled out. Serum ferritin, another iron-bearing protein, is also clinically important.

With conditions of high iron an aggressive program of iron removal by a health care provider is advised. Reducing consumption of iron-rich foods and regular blood donation can help decrease iron stores. Detoxification support efforts including adequate fiber for optimal gut transit and supplemental iron-free mineral support to antagonize iron accumulation are recommended.

As one effect of excess iron may be to increase the production of free radicals or oxidative stress, it is prudent to increase antioxidant protection by consuming an antioxidant-rich diet and also by taking supplemental antioxidants such as Extension Antioxidant II. Deviations in iron levels, low or high, lead to health issues. Checking the body’s iron status is easily accomplished through routine blood chemistry analysis yet is often overlooked and excluded from testing. Make sure it is included in your next blood work-up.

Source:  Iron Overload Can Result in Poor Health