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Friday, 1 April 2022

China Crushed Covid. But Covid Zero Could Crush China

A new wave of infections is highlighting the growing cost of China’s zero-tolerance virus policy

Updated on


Workers from a public service organization deliver vegetables to residents of a Shanghai neighborhood in lockdown on March 29. Photographer: Hector Retamal/AFP/Getty Images


China’s Covid Zero strategy has been drastic and effective, saving lives and keeping the economy on track. But a new wave of virus cases is highlighting the growing costs of that approach – as well as the perils of any attempt to change it. 

Authorities are fighting to curb the spread of the omicron variant among a population that lacks natural immunity and only has access to home-grown vaccines that are less effective than some of the global alternatives. Shanghai – the country’s financial center – is locking down just weeks after the technology hub of Shenzhen was forced to do so.

For the rest of the article refer to the link below ...

Source:

https://www.bloomberg.com/news/features/2022-03-31/china-s-covid-zero-strategy-what-could-xi-jinping-do-next

Saturday, 26 March 2022

Is taking a daily Aspirin a good idea?

What was recommended years ago might no longer apply today for many people. Here's why.



This article was originally published in the Montreal Gazette


I have been asked a lot lately about the recent draft recommendation from the United States Preventive Services Task Force that adults over 60 do not need to take a daily Aspirin. 

While this might be surprising to some, it is actually based on nearly a decade of research and is not really news to most medical people. But, before people start throwing away their medication, we should remember that there is a difference between people who are trying to prevent a heart attack and those who have already had one.

In the medical world, we make a distinction between primary prevention and secondary prevention. In primary prevention, you are trying to prevent a healthy person from getting sick, whereas in secondary prevention you are dealing with someone who is already sick and trying to prevent them from getting worse. In secondary prevention — people who have had a heart attack or stroke or some other form of vascular disease in the past — Aspirin therapy is clearly beneficial.

But many of the people taking Aspirin do not have prior cardiovascular disease. These primary prevention patients were probably told to start Aspirin at some point or might have even started it themselves because of the often-repeated maxim that everyone over the age of 50 should take a daily Aspirin. 

In the past, some studies did suggest a benefit for a baby Aspirin once a day. Studies like the Physicians’ Health Study and the Hypertension Optimal Treatment trial showed a benefit to daily Aspirin and are likely responsible for the common perception that people, especially those with risk factors, should be taking it for primary prevention.

But the reality is that these studies are decades old and the evidence base has not held up over time. More contemporary studies have not shown a benefit to daily Aspirin for primary prevention, and a 2009 meta-analysis by the Antithrombotic Trialists Collaboration as well as a more recent 2019 meta-analysis in JAMA both showed the benefit to Aspirin therapy was minimal and largely offset by the increased risk of bleeding.

It is important to remember that these studies are not suggesting that Aspirin does not work or that the prior evidence is wrong. But Aspirin does increase the risk of bleeding, and for most patients, the benefit they draw from Aspirin is too small to justify the risk. 

Patients with prior heart disease are at higher risk and therefore draw more benefit from it. But patients with no history of cardiovascular disease, even those with risk factors, are too low-risk to benefit.

It might seem curious to people that earlier studies showed a benefit while more recent studies did not. The reality is that the medical landscape was very different in the late 1980s and early ’90s. Most medications we use today did not exist back then and those in use were not that good by today’s standards. People smoked more and many were walking around with blood pressure, blood sugar and cholesterol values that were much higher than we consider normal today.

So it isn’t that Aspirin stopped working, or that the earlier studies were wrong. The reality is that people today are at much lower risk for heart disease and stroke than they used to be because we are now better and more aggressive at treating their risk factors. Patients are lower-risk today and simply draw much less benefit from a baby Aspirin, hence the USPSTF recommendation.

There might be some primary prevention patients who are at particularly high risk for whom the cardiovascular benefit of Aspirin outweighs the bleeding risk. But for the majority of people, this is not the case. Given that patients often complain about taking too many pills, if they are truly primary prevention patients, the daily baby Aspirin could be one pill their physicians can stop.


@DrLabos


https://www.mcgill.ca/oss/article/health-and-nutrition/taking-daily-aspirin-good-idea

Is there any point in drinking oxygenated water? Simple answer. No!








Oxygen is critical for life and that also makes is susceptible to chicanery. If oxygen is so essential that the brain is permanently injured after just four minutes of deprivation, then surely more must be better! That’s the argument used by sellers of “oxygenated water” who often target athletes with claims that their product can improve athletic performance. 

Well, all water is actually oxygenated water because oxygen from the air dissolves in water, although not to a great extent since its solubility is only about 25 mL per liter. 

Still, this is enough for fish to extract with their gills to sustain life. More oxygen can be squeezed into water under pressure, which is exactly what the “oxygenated water” people do. 

However, most of this oxygen escapes into the air as soon as the pressure is released by opening the bottle.

Whatever dissolved oxygen remains is inconsequential since we do not breathe through our gut. Only a trace of the trivial amount of oxygen in the water will pass through the intestinal lining into the bloodstream, which is already saturated with oxygen anyway. 

The most salient point is that a single breath of air contains more oxygen than a liter of oxygenated water. A single breath is about 500 mL of air, of which is roughly 20% or 100 mL is oxygen. 

A sampling of a variety of oxygenated waters reveals an average of about 10 mL oxygen per 100 ml of water. 

Clearly, even if the oxygen from the water were absorbed, it would be less than taking an extra breath.

Of course, in science we do not go by theory, but by experimental evidence. And a number of studies clearly show that drinking oxygenated water has no effect on any sort of performance. 

Subjects performing standard maximal cardiopulmonary exercise tests drank either regular water or oxygenated water and there were no significant differences in results. Furthermore, participants were unable to identify the type of water they had consumed.

Often there is even more absurd hype piled on oxygenated water. There are claims that the oxygen content of the atmosphere is decreasing due to pollution, so we must supplement our intake with “superoxygenated water.” Total nonsense. 

Then there are these stupefying statements: “The oxygen is stabilized in micro-encapsulated water clusters.” “Our patented method of expansion and contraction of the water molecules several times per minute allows more oxygen consumption while taking on donor electrons.” “We use monoatomic oxygen in addition to other salutary forms of oxygen: O2, O4, O5, O6 and O7 which is less than half the diameter of regular diatomic oxygen.” Absolute mind-boggling gobbledigook!

For the cherry on top, these oxygenated waters are often sold in health food stores in an aisle next to dozens of types of antioxidants that claim to confer eternal health by neutralizing those dastardly free radicals generated by the body’s use of oxygen. 

I hope we have now thrown enough cold water on the hot hype of oxygenated water.


@JoeSchwarcz

https://www.mcgill.ca/oss/article/health-and-nutrition-you-asked/there-any-point-drinking-oxygenated-water