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Showing posts with label Embolism. Show all posts
Showing posts with label Embolism. Show all posts

Tuesday, 17 May 2022

Pancreatic Cancer: Four sensations in the leg could be among ‘first clues’ signalling 'lethal' cancer

 THE ILL-DEFINED nature of cancer symptoms can significantly delay referrals, so keeping well-informed of warning signs is crucial. According to recent findings, however, up to 70 percent of cancer patients are unaware of having an increased risk of blood clots. What's more, deep vein thrombosis (DVT) is sometimes the first clue of pancreatic cancer, which is notoriously difficult to treat.

Cancer is a disease of the cells and organs that is fast-spreading by nature. One surefire way to treat the condition is to catch it during the initial stages of its development. But pancreatic cancer, due to its location deep inside the body, is notoriously difficult to pick up at the outset. Four clues in the legs could be among the first signs of the disease, according to health bodies.

Pancreatic cancer has a unique ability to induce blood into a hyper-coagulative state.

In other words, the blood of patients with pancreatic cancer has an abnormal tendency to coagulate, which confers a higher risk of blood clotting.

Therefore, a clot in the leg is sometimes among the first clues that someone has pancreatic cancer, according to the Cancer Society.

“This is called a deep vein thrombosis," explains the health body.

Blood clots may be among the first signs of pancreatic cancer (Image: Getty )

“Symptoms can include pain, swelling, redness and warmth in the affected leg. Sometimes, a piece of the clot can break off and travel to the lungs, which might make it hard to breathe or cause chest pain."

A blood clot that travels to the lungs is medically known as pulmonary embolism or PE, which carries a high mortality risk.

“Still, having a blood clot does not usually mean that you have cancer. Most blood clots are caused by other things,” adds the Cancer Society.

It recently came to the attention of researchers that up to 70 percent of cancer patients are unaware they’re at a higher risk of DVT than the general population.

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The discovery emerged from the results of a survey carried out by the European Cancer Patient Coalition (ECPC), which assessed patient awareness and knowledge about cancer-associated DVT.

But aside from the fact that the condition is hard to pick up early, pancreatic cancer is also notoriously difficult to treat.

This makes pancreatic cancer the most lethal cancer in the body, according to Doctor Santhi Swaroop Vege, director of the pancreatic diseases group at Mayo Clinic.

In fact, the disease has an overall five-year survival rate of about seven percent, despite the marked medical advances effectuated in recent years.

CAncer

Symptoms of DVT pain include pain, swelling, redness and warmth in the affected leg (Image: Getty )

The disease is typically characterised by non-specific symptoms, such as weight loss, and abdominal pain, making early detection difficult.

The location of the pancreas in the body also makes it difficult to biopsy or image.

Doctor Vege told News Network: “That’s one of the biggest problems we face. Usually, these people will have indigestion, and acid reflux, before finally somebody thinks of a CT scan."

Indeed, the condition tends to be found at advanced stages when abdominal pain or jaundice has resulted.

Cancer: The signs and symptoms

Cancer: The signs and symptoms to look out for (Image: EXPRESS.CO.UK)

“At that time, it’s already late,” noted Dr Vege.
“If [the cancer] is localised to the pancreas and it is not involving the major structures, then the best treatment, of course, is resection - a big surgery.”
The best way to treat pancreatic cancer, however, is to remove the tumour completely before it spreads to neighbouring regions.
Men have a slightly raised risk of pancreatic cancer compared to women, which has partly been attributed to higher rates of smoking among men.

Tuesday, 9 August 2016

Binge watching TV can actually kill you, study finds

The danger could be even worse than is known – and is likely to increase as streaming services become popular, scientists suggest


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The researchers advised that 'binge viewing' should be treated like long-distance travel Getty

Watching too much television might kill you, according to a new study.
The hours of inactivity that are required to watch a TV series can raise the risk of dying from a blood clot in the lungs. For every extra two hours of TV watching per day, the risk of fatal pulmonary embolism was increased by 40 per cent, the researchers found. Watching five or more hours to TV programmes each day made people more than twice as likely to die than those watching less than 2.5 hours. 
The actual risk might be even worse than the findings suggest, because of the number of deaths from the disease. And the danger is set to increase yet further as people binge watch even more on streaming services.
The research has led scientists to warn that such habits – watching back-to-back episodes of a TV series – might be dangerous. 
The new study, conducted in Japan, looked at the TV watching habits of more than 86,000 people, studying them over time. Researchers followed people who were aged between 40 and 79 between 1988 and 1990, and then followed them through a 19-year period.
In all, 59 deaths from pulmonary embolisms were recorded. Pulmonary embolism is a dangerous condition, which can be made worse by not moving around. It will often begin with a clot elsewhere in the body that can move towards the lungs, clogging up vessels and killing people. More than a quarter who suffer them without having treatment can die. Deaths are often sudden.
"Pulmonary embolism occurs at a lower rate in Japan than it does in Western countries, but it may be on the rise,” said lead researcher Professor Hiroyasu Iso, from Osaka University. "The Japanese people are increasingly adopting sedentary lifestyles, which we believe is putting them at increased risk."
The scientists looked to account for the various other factors that could complicate the results, including levels of obesity, diabetes, smoking, and high blood pressure. They found that the otherprimary marker of pulmonary embolism, after the number of hours spent watching TV, was obesity.
The researchers expressed concern about the danger posed by binge watching. "Nowadays, with online video streaming, the term 'binge-watching' to describe viewing multiple episodes of television programmes in one sitting has become popular," Professor Iso said. "This popularity may reflect a rapidly growing habit." As such, people binge watching TV should act like they would on a plane, he said.
"After an hour or so, stand up, stretch, walk around, or while you're watching TV, tense and relax your leg muscles for five minutes," he advised.
The research did the study before mobile computers and unlimited streaming services became popular. The researchers said that more work would need to be done to work out whether those technologies pose even more of a danger.

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