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Showing posts with label Dopamine. Show all posts
Showing posts with label Dopamine. Show all posts

Thursday, 20 June 2019

Early brain 'signs of Parkinson's' found

Scientists say they have identified the earliest signs of Parkinson's disease in the brain, 15 to 20 years before symptoms appear.
20 June 2019
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Scans of a small number of high-risk patients found malfunctions in the brain's serotonin system, which controls mood, sleep and movement.
The King's College London researchers say the discovery could lead to new screening tools and treatments.
Experts said larger studies and more affordable scans were needed first.
Parkinson's is a progressive neurological condition affecting about 145,000 people in the UK.
The main symptoms are shaking, tremors and stiffness but depression, memory and sleep problems are also common.
Traditionally, the disease is thought to be linked to a chemical called dopamine, which is lacking in the brains of people with the condition.
Although there is no cure, treatments do exist to control symptoms - and they focus on restoring dopamine levels.
But the KCL research team, writing in Lancet Neurology, suggest that changes in the brain's serotonin levels come first - and could act as an early warning sign.

Brain imaging shows loss in serotonin function (blue/black areas) as Parkinson's disease progressesImage copyrightKING'S COLLEGE LONDON
Image captionBrain scans show a reduction in serotonin (blue/black area) as Parkinson's progresses

The researchers looked at the brains of 14 people from remote villages in southern Greece and Italy who all have rare mutations in the SNCA gene, making them almost certain to develop the disease.
Half of this group had already been diagnosed with Parkinson's and half had not yet shown any symptoms, making them ideal for studying how the disease develops.
By comparing their brains with another 65 patients with Parkinson's and 25 healthy volunteers, the researchers were able to pinpoint early brain changes in patients in their 20s and 30s.
These were found in the serotonin system, a chemical which has many functions in the brain, including mood, appetite, cognition, wellbeing and movement.

'Could open doors'

Lead study author Prof Marios Politis, from the Institute of Psychiatry, Psychology and Neuroscience at King's, said the abnormalities had been found long before movement problems had begun and before dopamine levels had changed.
"Our results suggest that early detection of changes in the serotonin system could open doors to the development of new therapies to slow, and ultimately prevent, progression of Parkinson's disease," he said.
Prof Derek Hill, professor of medical imaging at University College London, said the research provided some valuable insights but also had some limitations.
"Their results may not scale up to larger studies," he said.
"Secondly, the imaging method they used is highly specialised and limited to a very small number of research centres, so isn't yet usable either to help diagnose patients or even to evaluate novel treatments in large clinical studies.
"The research does, however, provide encouragement for the approach of trying to treat Parkinson's disease at the earliest possible stage, which is likely to be the best chance of preventing the rising number of people whose lives are destroyed by this hideous disease."
Dr Beckie Port, research manager at charity Parkinson's UK, said: "Further research is needed to fully understand the importance of this discovery - but if it is able to unlock a tool to measure and monitor how Parkinson's develops, it could change countless lives."

https://www.bbc.com/news/health-48691633

Friday, 5 February 2016

Fox News: Why you shouldn't give up coffee in 2016

Physician outlines health benefits on 'Fox & Friends'

Watch Anna Kooiman, Clayton Morris, and Pete Hegseth talk about Apple News, Nutrition, and Nutrition Fitness on Fox Friends.



https://www.youtube.com/watch?v=0VAai0wUyiE

Published on 1 Jan 2016


This post is on Healthwise

Monday, 9 February 2015

5 Natural Ways to Boost Your Sex Drive

Here are some ways to boost your desire without the nasty side effects of drugs:

November 27, 2008

intimacy, desire, couple
Here are some ways to boost your desire without the nasty side effects of drugs:

1. Exercise: Aerobic workouts improve blood flow to sex organs, and they can also boost your mood, pumping up "feel good" brain chemicals called endorphins. The increase in testosterone levels that arrives about one hour after working out can also leave you feeling sexier.

2. Relax: Too much stress increases the stress hormone cortisol, which causes testosterone to plummet.

3. Add a Little Novelty: Recent research shows that partaking in new and challenging experiences with your partner can boost the brain chemical dopamine, which helps fuel sex drive. This doesn't even need to be in the bedroom -- anything new is a good idea.

4. Consider Some Non-Drug Remedies: Ginkgo biloba has been used to treat sexual dysfunction. Vitamin B5 (pantothenic acid) could be useful, since it's critical for the manufacture of sex hormones in the adrenal glands. Choline may help to enhance levels of acetylcholine, a brain chemical that sends sexual impulses from your brain to your sex organs.

5. Inhale: Certain scents are known to be attractive, including the sweat of your partner.



Go to Healthwise for more articles

Saturday, 24 March 2012

Why drinking alcohol makes you fat

alcohol
Thursday, March 22, 2012 by: Fleur Hupston
See all articles by this author

(NaturalNews) There are many factors that affect weight loss, making the process more complicated than it may seem. The body produces different hormones in response to different types of foods and/or drinks. Losing weight is not only about calorie consumption but also about the types of foods and drinks consumed. Alcohol is one of the worst culprits when it comes to inhibiting weight loss because it disrupts the delicate balance of nutrition, fluid and hormones needed to lose fat.

Alcohol boosts cortisol, a fat-creating hormone

Drinking heavily or even occasionally increases the body's release of cortisol - the hormone that breaks down muscle and retains fat. This loss of muscle can mean a huge slowdown in one's metabolism, making it easier to gain weight. In addition, alcohol causes a drop in testosterone in men, a hormone which helps burn fat.

Alcohol also blocks the body from burning fat. Research published in the American Journal of Clinical Nutrition reported that fat metabolism can be reduced by as much as 73 percent after only two drinks of vodka and lemonade in a one-hour time period. In effect, alcohol shuts down the body's ability to access fat stores for energy. The body needs to be well-hydrated in order to build muscle and burn fat. Alcohol has the effect of dehydrating the body.

Drinking often accompanies irresponsible eating


Because drinking often puts one in a relaxed party mood, it is easier to indulge in snacks, potato chips and other unhealthy party foods -- the more one drinks the less one seems to care.

Alcohol is a powerful appetizer. An aperitif is often offered in restaurants to stimulate the appetite. Research has shown that there is a definite correlation between the amount of alcohol consumed before a meal and the amount of food eaten and that people eat more when they have beer or wine with their meal. Since alcohol causes the brain to release dopamine, the pleasure and addiction hormone, the result is an often addictive desire for more alcohol and food. This means one is hit with a double whammy when it comes to gaining weight: excess calories come from both the alcohol and the extra food that is usually consumed as a result of a stimulated appetite.

Alcohol is high in calories

Alcohol comes with very little nutritional value but is very high in calories. It is very easy to knock back a 200ml glass of wine but that is equivalent, in calories, to eating 25ml (5 teaspoons) of butter. Seldom do people stop at one glass of wine or one beer, and mixing alcohol with sugary mixers such as lemonade means even morecalories as the drink now contains sugar and alcohol.

Simply put, alcohol consumption on a regular basis and weight loss don't mix.

Sources for this article include:

American Journal of Clinical Nutrition, November 1999, Article De
novo lipogenesis, lipid kinetics and whole-body lipid balances in
humans after acute alcohol consumption, 928-936, Scott Q Siler,
Richard A Neese and Marc K Hellerstein

Physiological Behavior, March 200;81(1)51-8, article
Dose-dependent effects of alcohol on appetite and food intake, Caton
SJ, Ball M, et al.

http://www.jsad.com


About the author:
Fleur Hupston is a professional freelance writer. She is passionate about natural, healthy living and is currently studying to be a naturopath. She divides her time between studying, writing and home-schooling her children.


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