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Showing posts with label TSH. Show all posts
Showing posts with label TSH. Show all posts

Thursday, 7 July 2016

How Food Can Improve or Worsen Your Thyroid Function

Thyroid Function

Some people with thyroid issues are told certain foods might aggravate the problem. With all the conflicting information out there, it can get pretty confusing. The good news is, in the right amounts, even cruciferous vegetables are good for you. Here’s the scoop on your thyroid, what it does and how to ensure it functions at its best.

June 27, 2016 

Story at-a-glance

  • Every cell of your body uses thyroid hormones; they balance your metabolism, take in iodine and regulate your metabolism while interacting with all your hormones
  • Iodine can only be obtained through your thyroid and is directly involved in the development of your skeleton, brain and other crucial parts of your body
  • Weight gain, hair loss and fatigue are symptoms of low thyroid. Selenium, tyrosine and deiodinase enzymes are elements that can bring it into balance
  • Scientists are shifting from thinking of foods in “negative” terms in regard to the thyroid, instead focusing on connecting people with the nutrients they need for their individual thyroid function
By Dr. Mercola
With all the conflicting information out there pertaining to your thyroid, especially regarding what to eat and what to stay away from, it may be confusing. And when trying to ferret out the facts from most conventional health practitioners, the contradictions can get frustrating.
You might hear, “Stay away from cruciferous vegetables because they might prevent your system from absorbing iodine,” or, “Don’t drink coffee because it could block your thyroid hormone replacement medication.”
One important thing to know about your thyroid is how central it is to your overall health, so ensuring it’s operating properly is critical. Just as importantly, hypothyroidism is often manageable via your diet.

What’s Your Thyroid For?

The butterfly-shaped thyroid gland straddling your windpipe, right under your larynx, is the “mainframe” that regulates your metabolism, controls virtually every function of your body and interacts with all the other hormones, from your insulin to your sex hormones.
Thyroid cells are the only cells in your body that can absorb iodine. Your thyroid gland takes iodine from foods — the only way iodine can be obtained — combines it with an amino acid called tyrosine and converts it to three types of hormones: triiodothyronine (T3), thyroxine (T4) and diiodothyronine (T2).
T3 and T4 are then released into your bloodstream for transport throughout your body, where oxygen and calories convert them to energy.1 Every cell of your body uses thyroid hormones, so thyroid-related symptoms can vary.

How Thyroid Issues Are Diagnosed: Symptoms, Tests and Complications

There are two main disorders related to the thyroid gland. Hypothyroidism, when your thyroid gland doesn’t produce enough thyroid hormone, is the most common, and often linked to iodine deficiency. Symptoms include:
Cold sensitivity
Hair loss, including eyebrows
Rough skin; dry, tangled hair
Lethargy
Weight gain
Constipation
Hypoglycemia
Memory loss
It should be noted, though, that there are dozens of other seemingly unrelated symptoms of hypothyroidism, such as:
Fallen arches
Asthma
Psoriasis
Neck pain and stiffness
Carpal tunnel syndrome
Hoarseness
Pale skin
Vertigo
Overactive thyroid, or hyperthyroidism,2 often called Graves’ Disease, is sometimes described as your body attacking its own thyroid. In some instances, its most common symptoms are opposites of those caused by underactive thyroid:
Restlessness and irritability
Weight loss
Brain fog
Frequent bowel movements
Irregular heartbeat
Protruding eyes
Several tests to get to the bottom of a thyroid imbalance include thyroid antibody, basal body temperature or TSH (thyroid-stimulating hormone) testing. However, laboratory testing for thyroid issues is sometimes problematic.
As many as 80 percent of people with hypothyroidism fail to register as such with standard testing. According to The George Mateljan Foundation, a non-profit foundation that shares scientifically proven information about the benefits of healthy eating:
“Most physicians use outdated reference ranges when testing thyroid function. Also, studies have demonstrated that standard thyroid tests do not correlate well with tissue thyroid levels, which causes inaccurate diagnoses.
Most physicians and endocrinologists believe TSH is the best indicator of the thyroid function of an individual. However, someone can suffer from a significantly slow thyroid despite having a normal TSH, free T3 and free T4.
Some will test for T3. People can also have low T3 and show normal T4 and normal TSH. Many practitioners do not realize that this indicates a selenium or zinc deficiency, rather than a problem with the thyroid.3
Naturopaths and doctors with a more holistic approach tend to understand the importance of examining a patient’s symptoms in combination with the tests.

Main Minerals: Why Iodine, Selenium Are Important for Your Thyroid

Iodine is directly involved in the development of your skeleton, brain and other crucial parts of your body. According to Organic Lifestyle magazine:
“Iodine is a trace mineral found primarily in seafood, seaweed, plants grown in iodine-rich soil, unrefined sea salt and iodized table salt. Many people do not get enough iodine, and contrary to popular belief, this includes many people in developed countries.
Iodine from iodized salt is poorly absorbed and is not a healthy choice for raising iodine levels in the diet. Refined table salt contributes to a host of health problems. Iodine is absolutely necessary for thyroid function, but too much iodine (especially iodine outside of food) can impair thyroid function as well.”4
It’s hard to overstate how important iodine is to prevent disorders such as thyroid disease and fibromyalgia. In the case of cancer, iodine induces apoptosis, meaning it causes cancer cells to self destruct.5
Good sources of iodine include sea vegetables, organic, grass-fed yogurt, raw and grass-fed organic cow’s milk, Celtic sea salt and eggs.
Selenium, important for thyroid health, helps decrease inflammation, regulate immune responses and prevent chronic diseases. It’s found in water, soil, wild-caught Alaskan salmon, Brazil nuts, dairy products, garlic, onions, tomatoes and sunflower seeds. One billion people in the world have a selenium deficiency.6
Tyrosine is an amino acid involved in nearly every protein in your body. It’s an essential part of the production of several brain chemicals, such as neurotransmitters and dopamine, regulating hormones such as the thyroid, and even affecting your mood.7
A few of the foods containing tyrosine, such as wheat and soybeans, are not healthy, especially for people with hypothyroidism. However, several good sources include almonds, bananas, wild-caught Alaskan salmon, organic free-range poultry, avocados, pumpkin seeds and organic, free-range eggs.

Eating Cruciferous Veggies Can Improve Dysfunctional Thyroids

You’ve heard it since you were a kid: eat your vegetables. For people with hypothyroidism whose doctors have advised them against eating cruciferous vegetables, it must come as a surprise to learn that ingesting radishes, cabbage, broccoli and kale can improve your thyroid function because they boost your glutathione levels.
In the 1950s, scientists examined foods with the possibility that, rather than playing a nutritive role, some might actually pose a negative risk, particularly in regard to the thyroid.
These they called goitrogenic foods, potentially causing a swelling in the neck called a goiter. Glucosinolates in cruciferous vegetables were implicated as a likely culprit. However, studies to that effect are scarce, as one article explains:
“In terms of human research, studies suggesting a strong link between cruciferous vegetables and thyroid disease are limited … The vast majority of the research supports the consumption of cruciferous vegetables to prevent thyroid cancer.”8
Additionally, deiodinase enzymes, central to the production of thyroid hormones, were discovered. Scientists have since modified their theory about cruciferous vegetables. Instead, the focus is connecting people with the nutrients needed for their individual, optimal thyroid function. According to the George Mateljan Foundation:
“Over the past 50 years … researchers have determined that there are no such ‘negative’ substances in food, but only health-supportive nutrients that are not a good match for certain individuals because of their unique health history and health status. Five decades of research have also determined that certain nutrients — like tyrosine, iodine, and selenium — play a unique role in thyroid health.”9
When examining your own nutritional needs, remember that small amounts are best, as too much of some foods, especially cruciferous vegetables, can prevent your body from absorbing iodine and otherwise hinder optimal thyroid function.

Other Foods for People With Underactive Thyroid

There are many more ways to expand the culinary options for those with hypothyroidism, particularly plant-based foods with plenty of antioxidants and electrolytes, such as sodium and potassium, including these (keep in mind that most fruits should be eaten sparingly by most people due to high fructose content):
Squash
Bell peppers
Carrots
Green beans
Peas
Tomatoes
Celery
Asparagus
Eggplant
Purple grapes
Mangoes
Pomegranates
Blueberries
Pineapples
Apples
Citrus fruits
Cherries
Apricots
Another nutrient good for your thyroid is niacin. A few of the foods with this nutrient not already listed include lamb and turkey.10

What Foods Trigger Thyroid Issues?

If you’re wondering about the fare that might bring thyroid troubles to your door, the worst ones have one thing in common: They’re not real. As noted by Mind Body Green:
“Refined, processed, homogenized, pasteurized, genetically modified, fortified, and artificially flavored (or colored or preserved) ‘foods.’ The key to fixing the body, not just covering up ailments or shifting symptoms, but truly fixing the body, is produce. The key to deteriorating your health is refined, processed foods.”11
In particular, the following, which are often found in processed foods, might be problematic. First and foremost:
  • Gluten: with any thyroid issues, the first thing to eliminate is gluten. It can cause inflammation, gastrointestinal malfunction, thyroid disruption and other problems.
  • Non-Fermented Soy: no matter how many “natural” soy products claim to be good for you, soy may alter hormone function, especially in women. A plethora of studies indicate that soy phytoestrogens can damage your thyroid, as well as cause cognitive decline
  • Genetically Engineered (GE) Foods: genetically engineered foods may trigger both Graves’ and Hashimoto’s disease by eroding your gut lining.
  • Brominesbromine is a processed, endocrine-disrupting food additive often found in the flour used in bread and baked goods, sodas, sports drinks, toothpaste, mouthwash, plastic computer parts, upholstery and pesticides sprayed on strawberries.12
Good nutrition goes a long way toward helping to manage and even reverse the symptoms of hypothyroidism. As always, it’s best to obtain your nutrition from foods rather than resorting to supplements, if possible.
http://articles.mercola.com/sites/articles/archive/2016/06/27/foods-good-for-thyroid.aspx

Sunday, 17 January 2016

Demystifying diagnostics: Blood tests you may or may not need

Some doctors can go overboard with diagnostics. Others don’t seem to take every precaution you might expect when you’re concerned about your health.

Dr. Michael Cutler

Phlebotomist Drawing Blood
My patients often come asking for blood tests for a general health assessment. It’s part of the annual health “physical.” I think of blood tests for screening as basic, more advanced, and in-depth for disease risk profiling.
Having a little information about the different types of tests available to you may ease your mind and help you be the best patient advocate for yourself or others.

Tier 1 tests

The first and most basic screening blood tests I usually order for my patients with no known disease are the following:
CBC: the complete blood cell (CBC) analysis measures your red and white blood cells. Your red blood cells carry oxygen throughout your body; the most common disorder here is anemia. Your white blood cells are a measure of your immune system status and are rarely abnormal when you are not fighting an infection. White blood cell cancer is known as leukemia.
CMP: The comprehensive metabolic panel (CMP) reveals the general function of your liver, gall bladder, and kidneys. It measures your blood sugar, mineral electrolytes (sodium, chloride, potassium, and calcium), acid-base balance, and blood protein (called albumin).
TSH: The thyroid stimulating hormone (TSH) is measurement of the pituitary hormone (from your brain) that controls the secretion of your active thyroid hormones T3 and T4 (from your thyroid gland). When your TSH level is low, it is generally an indicator of hyperthyroidism and you are expected to have elevated thyroid hormones circulating in your blood. However there is some recent science showing that genetic variances in a nearly a third of our population cause thyroid hormone function not to be accurately reflected by measurable TSH and thyroid hormone levels.
Lipid Panel: This is your basic cholesterol panel, showing your total cholesterol, LDL (low density lipoprotein) or “bad” cholesterol, and HDL (high density lipoprotein) or “good” cholesterol, with ratios. You must fast 8-12 hours preceding this test for it to be accurate. The lipid panel has general implications for cardiovascular disease (CVD) risk. However, elevated “bad” cholesterol or low “good” cholesterol levels have a poor correlation based on more recent scientific studies. The incidence of heart attacks among individuals with normal cholesterol levels is more than individuals with abnormal lipid levels.

Tier 2 tests

If you have an abnormal result from basic screening blood tests or if you want a more thorough assessment of your disease risk, I like to order these additional blood tests:
HbA1c: your blood glucose level can be in the normal range, especially if you were fasting 12 hours prior the blood draw. You can have pre-diabetes or even long-standing diabetes and miss it on a fasting specimen. The HbA1c test reveals your average blood sugar level over the past 3-months. Results ranging from 5.7% to 6.4% demonstrate pre-diabetes (glucose intolerance), which means you are not metabolizing sugar normally and really should make some serious improvements in your diet and exercise (or begin the medication Metformin). In the Diabetes Prevention Program, 58% of participants prevented progression to diabetes through diet and exercise interventions (compared to 31% who prevented progression to diabetes by taking Metformin).
Vitamin D: Approximately 75% of American adults are deficient in Vitamin D. I find this to be accurate from routinely testing my patients. Therefore, I test the 25-Hydroxy Vitamin D level, and if low (below 30), supplementation will bring it into the optimal range (50-100). Click here for my article about Vitamin D deficiency posted earlier this year.
Vitamin B12 & Folate: Elevated vitamin B12 can be an indicator of the common MethylTetraHydroFolateReductase (MTHFR) gene polymorphism which causes a host of symptoms of illness and can be corrected by supplementing with methylated folate or methylcobalamine. Click here for my article, “Coaching your genes to do a better job.”
Free T3 and T4: Triiodothyronine (T3) and thyroxine (T4) measurements will tell you how much thyroid hormone is circulating in your blood. It may not necessarily tell you if it is effective in your thyroid-sensitive organ tissues.  Click here for my recent article, “Low thyroid function causes high health risks.”
Cortisol: A serum cortisol level will give you an idea of adrenal stress/fatigue and the need for treatment. Click here for my article “Tired, depress and hurting? Could be adrenal fatigue.”
Testosterone, estradiol, progesterone: Low testosterone in men or women is treatable. Low estrogen or progesterone, or estrogen dominance is also treatable safely from natural sources. Click here for my articles on testosterone. And here for my previous articles on menopause.
C-reactive Protein: This is produced by your liver and indicates inflammation in your body. Although non-specific, an elevated level is considered a “marker” for disease.
Saliva hormones: cortisol (8am, noon, 4pm, bedtime), melatonin, DHEA-Sulfate, free and total Testosterone, Estradiol, and Progesterone. I have used Access Medical Labs but there are several other specialty laboratories that do these, but are typically not covered on insurance.
In my next article (see below) I’ll explain more very important tests for disease profiling.
http://easyhealthoptions.com/demystifying-diagnostics-blood-tests-may-may-not-need/



Doctor’s guide to advanced blood tests



Nurse with vials for blood samplesYou’ve probably had your fair share of blood tests and other diagnostics at your doctor’s office. Last week, (see the article preceding this) I shared some that are rather routine so you’d have a guide to understanding them better.
In this article let’s look at more advanced blood tests your physician can order to screen for illness — illness that is developing but not yet showing signs or symptoms.

Tier 3 tests

When you consider that 1 out of 3 U.S. adults has some form of heart disease and approximately 50% of people who experience a heart attack have “normal” cholesterol results, it makes sense to use the most accurate and predictive testing for risk assessment. Chronic illness doesn’t manifest until years after it has been developing inside you. So let’s now consider the most accurate blood tests (bio markers) available for early detection of risk for heart disease, inflammation, and diabetes.
Because these tests are newer, ask your doctor to order them from your usual lab company and bill it to your insurance. Alternatively, you can go directly to specialty lab companies to get these and bill your insurance or pay out of pocket, and these companies are “in-network” providers for a growing list of insurance companies. Specialty lab companies include True Health DiagnosticsGenova and SpectraCell.

Heart disease tests

Oxidized LDL measures the amount of your sticky or “oxidized” LDL cholesterol. As I mentioned previously, measuring all LDL does not correlate well at all with heart disease risk. Oxidized LDL is a much better predictor of progression towards arteriosclerosis (“hardening of the arteries”). [1]
LDL particle number and size is another highly valuable piece of information regarding your heart disease risk. The more particles of LDL and HDL you have, the higher your risk for arteriosclerotic plaque to build up inside your heart arteries. You can have low LDL cholesterol (LDL-C), but a high LDL particle (LDL-P) count, which is a hidden risk for cardiovascular disease. Also, when HDL-P count is low, you are trending towards insulin resistance. Also, smaller LDL-P size can more easily enter the blood vessel wall and cause heart disease. Worse, small dense LDL can more easily get into the artery wall to develop arteriosclerosis and can be measured too. Nuclear magnetic resonance (NMR) spectroscopy is the preferred way to measure LDL particle concentrations (LDL-P). [2]
Apolipoprotein B is another way to estimate LDL particle concentration. [3] Low levels correspond with increased risk of plaque build-up, or arteriosclerosis. Dietary measures and an active lifestyle improve these measurements.
Lipoprotein (a) is a genetic risk for heart disease that is does not improve much with cholesterol medications. The Lp(a) test is especially valuable for you if you have a personal (or family) history of heart disease with a normal LDL-C level.

Tests for inflammation

High levels of blood fats as well as insulin resistance trigger inflammation in your arteries. Inflammation inside your heart artery walls is what causes plaque build-up, known as arteriosclerosis. This is why diabetes is now considered a “cardiovascular disease risk equivalent” equal in importance to having already had a heart attack.
Lipoprotein-associated phospholipase A2 measures inflammation inside your artery wall; high levels indicate the risk for rupture and can be lowered by diet, exercise, fish oil supplementation, and blood pressure control.
Homocysteine is an amino acid that becomes elevated when there is heart vessel inflammation. One cause is a MTHFR gene abnormality. See my article on MTHFR gene SNP entitled “Coaxing your genes to do a better job” found online here.
Fibrinogen is a blood clotting protein. Inflammation activates this to become elevated, leading to worse risk of arteriosclerosis, while consistent exercise can lower this.
Brain Natriuretic Peptide (BNP) is an enzyme that becomes elevated in several heart or lung stress conditions. It is a marker of congestive heart failure.

Diabetes risk tests

Adiponectin is a hormone from secreted from your fat cells to control body fat storage and if it gets too low from eating too many sugar foods you are not well protected from heart disease. This is the earliest detection of trending towards diabetes, even before other tests show abnormalities (glucose, HbA1c, Insulin).
Insulin: when fasting insulin is rising and adiponectin is low you are even further along the path to diabetes. Your blood sugars and HbA1c levels may still be normal.
Proinsulin: This is a measurement of insulin your pancreas is producing. By the time your proinsulin levels are on the rise (along with low adiponectin, high insulin and rising post prandial blood sugar levels), you’re clearly into insulin resistance and pre-diabetes even though your fasting blood sugar may still be in the normal range.
Fructosamine shows an average of blood sugar control over 2 weeks. Remember that the HbA1c test (previous article) measures blood sugar average over 3 months.
Leptin is the hormone responsible for your appetite and feeling full. This may become less functional when you are insulin resistant.
Free Fatty Acids (FFAs): These are elevated the more fats in your diet turn into triglycerides and may cause insulin resistance to develop. It is a measurable link between obesity and insulin resistance.
While these “advanced” blood tests are leading edge, they don’t uncover another aspect of disease that often gets completely overlooked: intestinal health. In my next article I’ll look further into intestinal health, this important link to chronic disease development, and ways to measure your intestinal and immune system health.
To feeling good each day,
Michael Cutler, M.D.
Easy Health Options
[1] http://www.truehealthdiag.com/wp-content/uploads/2015/09/Diabetes-2004-Holvoet-1068-73-oxLDL-mets.pdf
[2] Jeyarajah EJ, Cromwell WC, Otvos JD. Lipoprotein particle analysis by nuclear magnetic resonance spectroscopy. Clin Lab Med. 2006;26:847–70. [PubMed]
[3] Sniderman A, Vu H, Cianflone K. Effect of moderate hypertriglyceridemia on the relation of plasma total and LDL apoB levels. Atherosclerosis. 1991;89:109–16. [PubMed]
http://easyhealthoptions.com/doctors-guide-advanced-blood-tests/


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