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Showing posts with label Blood sugar. Show all posts
Showing posts with label Blood sugar. Show all posts

Thursday, 2 August 2018

Keep AWAY from the cornflakes: Even 'healthy' people experience dangerous blood sugar spikes after a bowl of cereal, study shows

  • New continuous blood glucose monitors reveal a stream instead of a snapshot of blood sugar levels throughout the day 
  • Even those considered 'healthy' had significant spikes in their levels after eating certain foods, like carbohydrates 
  • These spikes have been linked to cardiovascular risks 
  • Stanford University study authors created three new categories of non-diabetic people who 'misregulate' glucose 
  • About 80 percent of people had significant spikes after eating cornflakes and milk for breakfast  

Your morning bowl of cornflakes may be sending your blood sugar into the stratosphere, new research suggests. 
Everyone's blood glucose levels ebb and flow throughout the day based on our activity levels, they kind and quantity of calories we consume, metabolism and much more. 
People who have diabetes or prediabetic are most classically defined by their bodies' struggle to regulate glucose. 
But a new Stanford University study has revealed that even most people who would otherwise be considered 'healthy' have significant glucose spikes throughout the day - especially if their first meal is cornflakes and milk. 
A spoonful of high blood sugar: Stanford University tests of continuous blood sugar monitors revealed high spikes in glucose levels after 'healthy' people eat cornflakes with milk
A spoonful of high blood sugar: Stanford University tests of continuous blood sugar monitors revealed high spikes in glucose levels after 'healthy' people eat cornflakes with milk
The discovery was an unexpected result of the institution's tests of new constant glucose monitoring devices. 
With older glucose monitors, doctors have typically recommended that people with type one diabetes test their blood any where from four to 10 times a day. Those with type two most commonly measure their levels after each meal and once before bed.
But continuous monitors, typically consisting of a tiny implant just beneath the skin that transmits to a phone or watch, give a comprehensive view of glucose fluctuations, rather than a series of snapshots. 
'Soon, you're going to see a lot more of them, they're going to be incredibly widespread,' much like fitness trackers such as the Apple Watch or Fitbit, senior study author Dr Michael Snyder told Daily Mail Online. 
As he and his team followed a group of study participants - some 'healthy,' others prediabetic and others diabetic - for four years, they saw something surprising. 
'Lots of 'normal' people spiked very high, as high as diabetics,' said Dr Snyder. 
'There are a lot of people running around with spiking glucose levels who have no idea that these spikes have been associated with cardiovascular disease and things like that.'  
Based on the treasure trove of information that Dr Snyder and his team gathered from the glucose monitors on their 57 subject, they categorized people into three self-explanatory groups: high spikers, medium spikers and low spikers.  

WHAT ARE THE FIVE NEW TYPES OF DIABETES?

For decades the disease has been considered to be two different forms - type one, an autoimmune disease in which people stop producing insulin, and type two, in which the body becomes resistant to insulin.
But now a major project in Sweden and Finland has found type two diabetes should actually be categorised as four different diseases.
The researchers, led by experts at Lund University, said the findings should prompt a ‘paradigm shift’ in the way people treat diabetes.
Cluster 1. Severe Autoimmune Diabetes - which until now has been known as ‘type one’ diabetes - is an autoimmune disease in which people stop producing insulin. Usually strikes in childhood but can emerge in adults. Requires insulin injections for life.
Cluster 2. Severe Insulin-Deficient Diabetes - young people often misdiagnosed as having type one, but whose immune systems are fine. Actually a variant of type two diabetes, but often of a healthy weight. High blood sugar, low insulin production and moderate insulin resistance.
Cluster 3. Severe Insulin-Resistant Diabetes - is predominantly linked to obesity and severe insulin resistance.
Cluster 4. Mild Obesity-Related Diabetes - includes obese patients, but is less serious and includes people who fall ill at a relatively young age.
Cluster 5. Mild Age-Related Diabetesis the largest group, with 40 per cent of all patients, and consists mostly of elderly patients.
These spikes occurred after people at all kinds of foods, and it seems that not everyone experiences the same extremity of spike with the same foods.l  
Of course, most people with diabetes or who were prediabetic - meaning have somewhat elevated blood glucose in general and are already somewhat insulin resistant - fit into the 'high spiker' category. 
But so did many people who previously thought they were in the normal range. 
Earlier this year, Swedish researchers described five types (or 'clusters' as they called the groups) of type two diabetes. 
Dr Snyder thinks that his research suggests we need more granular divisions still in order to properly diagnose and treat people as individuals. 
'That's just the tip of the iceberg,' he said. 
'We think there are many more. Their number is five, and I think that's going to expand as we try to really pick people apart for what's wrong with them glucose-wise.'
Doing so could help to really fine tune treatment and dietary plans to optimize glucose levels for everyone - not just those who have been traditionally considered diabetic. 
But good starting place for us all might be to cut the cereal out of our morning routine, the Stanford study, published in Plos, suggests. 
Dr Snyder's team separated out a subgroup of 30 participants and put them on a controlled diet. For their research purposes, the most important meal of the day was breakfast (when the 'tank is on empty,' and the leftovers of the last meal are most likely to have already been metabolized).
The participants alternately ate a protein bar, a peanut butter sandwich or cornflakes with milk. 
Surprisingly, it was the cornflakes and milk that sent most people's blood sugar through the roof. In fact, 80 percent of people experienced high spikes after eating the seemingly simple breakfast. 
Dr Snyder aims to figure out what distinguishes high spikers from low ones, and how extensive the health benefits of keeping glucose spikes to a minimum are. 

But for now there is at least one quite clear take away from the study: 'The data are right in front of you, 80 percent of people are spikers, so can’t say I’d run around endorsing eating cornfalkes with milk. I'm not sure that would be in anyone's best interest,' Dr Snyder said.  
http://www.dailymail.co.uk/health/article-6008603/Even-healthy-people-experience-dangerous-blood-sugar-spikes-bowl-cereal-study-shows.html

Thursday, 19 July 2018

Blood sugar and glucose levels: what they mean, and what they should be


Your blood sugar level is in constant flux, depending on what you've eaten, when you ate it, and what you did afterwards. A finger-prick blood test can ascertain your level at any moment in the day – it's a crucial tool for diabetes sufferers, as they need to manage their body's insulin response.

Sugary drinks
How much sugar is in your diet? CREDIT: ANTHONY DEVLIN/PA
In people with diabetes, explains Dr Soon Song, a consultant physician and diabetologist at BMI Thornbury Hospital in South Yorkshire and Sheffield Teaching Hospitals NHS Foundation Trust, the blood glucose levels are raised both before and after a meal.
“In a healthy individual without diabetes,” he says, “the body produces the correct amount of insulin from the pancreas to normalise the blood glucose level. But in diabetes, the pancreas does not produce enough insulin and/or the body is not able to use the glucose effectively due to lack of responsiveness to insulin action (known as insulin resistance).

“So the blood glucose level rises to abnormally high levels, which puts pressure on the body’s organs and nerves. causing permanent damage.”

What is blood sugar and glucose?

Sugar is a carbohydrate found naturally in food. There are different types of sugars: glucose belongs to a type of sugar called monosaccharides or simple sugar. It is the primary source of energy and the body tissues need glucose to function normally, especially the brain. “The terms blood sugar and blood glucose are often used interchangeably and refer to the amount of glucose carried in the blood,” says Dr Song.

What is a normal blood sugar level?

Understanding what is a normal blood sugar level is vital to diabetes prevention or management. Blood sugar level refers to the amount of glucose in the blood, sometimes known as blood glucose level; the concentration of glucose in the blood is expressed in mmol/l.
In healthy people without diabetes, your blood glucose level should measure between 4.0-5.5 mmol/l before a meal and should be less than 8.0 mmol/l two hours after a meal.
The blood glucose level is also measured by glycated haemoglobin, HbA1c, which gives information on the average blood glucose level over the last 2-3 months. A healthy person without diabetes should have HbA1c less than 42 mmol/mol.
Diabetes is diagnosed when the fasting blood glucose is greater than 7.0 mmol/l, random blood glucose greater than 11.1 mmol/l, or HbA1c greater than 48 mmol/mol.
A fasting blood glucose level between 5.5 and 6.9 mmol/l or HbA1c between 42 and 47 mmol/mol may indicate increased risk for type 2 diabetes, particularly those with obesity, family history of diabetes or from certain ethnic groups.

What are low blood sugar symptoms?

Low blood glucose is also known as hypoglycaemia. It is defined by blood glucose below 4 mmol/l.
“In the early stages of hypoglycaemia,” says Dr Song, “the body will react by releasing hormones such as adrenaline to warn that the blood glucose is going low so that actions can be taken to reverse the hypoglycaemia.
“This causes symptoms include palpitations, hunger, feeling warm or flushed, tremulous and sweaty.
“If the blood glucose falls lower, brain function will be affected resulting in confusion, irritability, aggressive behaviour, seizure and coma.
“Since the brain is highly dependent on glucose to function, frequent hypoglycaemia can cause cognitive impairment.”
Some people with diabetes may have hypoglycaemia unawareness where the warning symptoms are weak, especially during the early stages of hypoglycaemia. This usually occurs in those with long duration of diabetes, tight diabetes control or frequent hypoglycaemia. This condition is potentially dangerous as the patient is unaware the blood glucose is going low and therefore, not able to correct the low blood glucose at an early stage until it is too late when the brain function is affected. If untreated, prolonged severe hypoglycaemia can cause permanent brain damage. 
People can experience hypoglycaemia at night when they're asleep. Low blood glucose level can wake the person up or lead to headaches, tiredness and sweat-soaked sheets in the morning.

What are the symptoms of high blood sugar?

The symptoms of high blood sugar level occur when diabetes is uncontrolled, regardless of the type of diabetes. Typically, the patient experiences thirst, dry mouth, frequent urination, blurred vision and tiredness. In more extreme cases, weight loss can occur. 
Occasional mild periods of high blood sugar level are non-threatening. They can require treatment or return to normal levels on their own. But frequent or severe episodes can be dangerous and can lead to coma.

What happens if I don’t control my blood sugar?

Poorly controlled blood glucose levels can lead to health complications, warns Dr Song. “High glucose levels over a prolonged period, usually over several years, can damage the blood vessels in the eyes, kidneys, nerves and legs (peripheral vascular disease and gangrene). It can cause a heart attack or stroke. Apart from poor diabetes control, high blood pressure and high cholesterol levels also contribute to these complications. These risk factors are common in type 2 diabetes. Adequate treatment of the blood pressure and cholesterol levels are as important as managing the glucose control to reduce the complications.
“Type 2 diabetes is often not diagnosed in the early stages due to lack of symptoms. As a consequence, approximately 50 per cent of people with type 2 diabetes have some form of complications at diagnosis.”

How to monitor and test your blood sugar levels
At home, the blood glucose level can be checked by the person with diabetes using a finger prick test with a blood glucose meter. This method checks the glucose level in the capillary blood obtained from the finger prick.
“It is important that the finger is clean and not contaminated by any glucose-containing material when this test is done,” says Dr Song “as otherwise, it can lead to erroneous results. 
“This self-monitoring of blood glucose can help to guide diabetes treatment, especially with insulin injections, that will achieve a satisfactory glucose control.”

Do hot baths lower blood sugar levels?

There is evidence that hot baths do lower blood glucose levels. It could be a good alternative to exercise for some people who want to reduce their blood sugar levels. But doctors will point out that exercise is an important part of a healthy lifestyle.

Can diabetes affect your thinking?

 Diabetes is associated with cognitive impairment but not everyone with diabetes will experience this. Older people with diabetes have been found to lose cognitive ability faster than those without the disease.

https://www.telegraph.co.uk/health-fitness/body/blood-sugar-glucose-levels-mean-should/

Tuesday, 28 March 2017

Insulin Use as a Secondary Treatment for Type 2 Diabetes Linked to Heart Disease, Death

Patients with type 2 diabetes who take a combination of metformin plus insulin may be at higher risk for cardiovascular disease and death compared with those who take a combination of metformin plus sulfonylurea ...


By Staff Editor
Jun 10, 2014 - 4:37:02 PM

(HealthNewsDigest.com) - Patients with type 2 diabetes who take a combination of metformin plus insulin may be at higher risk for cardiovascular disease and death compared with those who take a combination of metformin plus sulfonylurea, according to a new study funded by the Agency for Healthcare Research and Quality (AHRQ) that appears in the June 11 issue ofJAMA. The study, a review of medical records from national databases, found a greater association between insulin as a second-line treatment and risk of death and cardiovascular disease than sulfonylureas as second-line treatment.

Adults with type 2 diabetes are typically treated first with metformin, an oral medication that helps reduce elevated blood sugar. When combined with exercise and diet modification, metformin alone can help many patients control their blood sugar levels, keeping the disease in check. However, some patients require a second drug, usually an oral medication such as a sulfonylurea or a self-administered injection of insulin to bring their disease under control.


"Type 2 diabetes is a serious condition affecting millions of Americans, and they and their clinicians need good evidence to make informed decisions about the best treatment options," said AHRQ Director Richard Kronick, Ph.D. "The findings of this report may surprise those who had considered insulin to be a preferred secondary treatment for diabetes in most circumstances. However, consistent with AHRQ's mission, our goal is to generate evidence on critical treatment issues like this one and broaden the information available for patients and clinicians to use."


In the new study, AHRQ-funded researchers led by Christianne L. Roumie, M.D., M.P.H., of the Tennessee Valley Veterans Affairs Medical Center in Nashville, analyzed records from databases at the Veterans Health Administration (VHA), Centers for Medicare & Medicaid Services and the National Center for Health Statistics. They studied more than 42,000 patient records and the National Death Index to assess the effects of insulin and sulfonylureas, the two medications most commonly prescribed in the study population as second-line treatment for diabetes.


The retrospective cohort study compared 2,500 VHA patients who added insulin to their metformin regimen with 12,000 VHA patients who added a sulfonylurea. On average, patients were about 60 years old, and about 35 percent had history of heart disease or stroke. The patients studied had been on metformin for an average of 14 months, and their average hemoglobin A1c count (a key indicator of success in controlling blood sugar) was 8.1 percent, which is higher than is preferred, when the second medication was prescribed.


The researchers identified patients who were taking one of two drug combinations: metformin-plus-insulin or metformin-plus-sulfonylurea. Then they compared the risks of heart attack, stroke or death for these patients. They found an association of metformin-plus-insulin to have a higher risk of cardiovascular events and death than metformin-plus-sulfonylureas, although harms were found for both regimens.


"Insulin has been shown to be a very good medication in achieving blood sugar control, and because of that, prior large studies have found that there is a reduced risk of developing diabetic kidney or eye disease," according to Dr. Roumie. "However, this study and others have shown that tighter glucose control doesn't necessarily have any benefit for heart disease, and these findings call into question recommendations that insulin is equivalent to sulfonylureas for most patients who can control their blood sugar with a second oral drug."


Dr. Roumie's research team also conducted a study published in 2012 on first-line treatments for adults with type 2 diabetes. In that study, which also was funded by AHRQ, the researchers compared the use of sulfonylurea with metformin for first-line treatment. They found that sulfonylureas, when used as a first-line treatment, increased patients' risk of death and cardiovascular events compared with metformin.


The new study looks only at second-line treatments. Together, these two studies of primary and second-line diabetes treatments can help clinicians better determine which medications are least risky for each patient, depending on the patient's clinical characteristics.


This study focused primarily on U.S. military veterans, and the study population was overwhelmingly white and male, so the study noted that there might be differences in the risks of using insulin as a secondary treatment in the broader population.. As a retrospective analysis of VHA medical records, the study is not a randomized controlled trial and thus does not determine definitively that insulin directly led to deaths and cardiovascular disease. More research is needed to determine if these differences exist and, if so, to what extent, researchers said. Insulin is a powerful drug and is an appropriate treatment when patients cannot control their blood sugar with oral agents alone, researchers said.


AHRQ is a research agency within the U.S. Department of Health and Human Services (HHS). Its mission is to produce evidence to make health care safer, higher quality, more accessible, equitable and affordable, and to work with HHS and other partners to make sure that the evidence is understood and used. For more information, visit www.ahrq.gov.

http://www.healthnewsdigest.com/news/Diabetes_Issues_640/Insulin-Use-as-a-Secondary-Treatment-for-Type-2-Diabetes-Linked-to-Heart-Disease-Death.shtml


Friday, 30 December 2016

The 25 Best Inventions of 2016

Every year, TIME selects the best inventions that are making the world better, smarter and—in some cases—a little more fun. In the past, we’ve featured everything from the real-life hoverboard to the desktop DNA lab. Here’s which ones made this year’s unranked list.


  • The Levitating Lightbulb

    flyte-floating-bulb
    Lucas Zarebinski for TIME
    Flyte / $349
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    Since he was a child, Simon Morris has been obsessed with making objects float in midair. At one point he even managed to turn a skateboard into a hoverboard, though as he recalls it, “I couldn’t ride on it.” Now he’s applying that same passion to Flyte, a lightbulb that relies on electromagnetism to levitate and spin, and on resonant inductive coupling—a technical term for wireless power ­transmission—to shine. Morris sees his design as a seamless blend of science and art honoring both pragmatists, like Thomas Edison, and dreamers, like Nikola Tesla. And consumers appear to agree: Morris says Flyte has sold so well since its official January launch that his team is planning to introduce a whole ecosystem of floating products, including a planter, Lyfe, which debuted in June. “We’re just scratching the surface,” he says.
  • The Folding Bike Helmet

    https://timedotcom.files.wordpress.com/2016/11/morpher-helmet.jpg
    Lucas Zarebinski for TIME
    Morpher / $119
    Like many cyclists, Jeff Woolf has been involved in a serious crash—one that might have killed him were it not for his helmet. So why, he wondered, do so many of his contemporaries refuse to wear one? Turns out, it’s mostly because they’re hard to carry around; they’re thick and bulky, and don’t fit into bags or backpacks. And that was a problem that Woolf, an engineer, knew he could fix. The result: Morpher, a bike helmet made from interweaved plastics that is just as strong as its traditional counterparts (it meets general safety requirements in both the U.S. and Europe), but flexible enough to fold almost totally flat, making it easier to transport. Woolf recently shipped the first units to his Indiegogo backers, who helped raise almost $300,000; he’s now in talks with stores too. “It’s inevitable that as more people take to the road on a bicycle, more people will have accidents,” Woolf says, adding that he hopes Morpher will save lives.
  • Solar Panels That Don’t Stick Out

    solar-roof-tesla-solarcity
    Tesla
    Solar Roof / Developed by Tesla and Solarcity
    Help the environment, save some money—and litter your roof with bulky metal boxes. That’s the dilemma home-solar-panel buyers have faced for years. Tesla’s response: the Solar Roof, a series of tiles designed to blend together while also harnessing the power of the sun. The product line, which will be available next year, is a collaboration between Tesla and SolarCity, a longtime provider of traditional solar panels. (The former is set to acquire the latter.) And although pricing information has not yet been released, SolarCity CEO Lyndon Rive is optimistic about Solar Roof’s potential. “It’s addressing a new segment,” he says, referring to the 5 million Americans who install new roofs each year, some of whom might want to go solar.
  • Shoes That Tie Themselves

    nike-hyperadapt
    Lucas Zarebinski for TIME
    Nike Hyperadapt 1.0 / $720
    Almost everyone who sees Back to the Future wants three things: a time-traveling DeLorean, a working hoverboard and a pair of self-lacing shoes. Now, thanks to Nike, the shoe dream is a reality. When wearers press a button near the tongue, the HyperAdapt 1.0s automatically tighten and loosen around their foot. And although this technology may sound frivolous, it’s not just for kicks: simplified shoe fastening could give athletes an edge during competition, and it’s especially useful for people with impaired motor function. “We’re already seeing powerful feedback” from the disabled community, says Tinker Hatfield, Nike’s vice president of design and special projects.
  • Soccer Fields That Fit Anywhere

    ap-thailand-bangkok-unusual-soccer-fields
    AP Thailand
    The Unusual Football Field / Developed by AP Thailand
    The Khlong Toei district in the heart of Bangkok is packed tight with buildings and people—which doesn’t leave much room to build new parks, let alone giant rectangular fields on which kids can play soccer. So real estate firm AP Thailand took a different approach. As part of a recent project, the company used aerial photography to find what developer Pattaraphurit Rungjaturapat calls “untended areas,” or unusually shaped patches of land that weren’t being used. Then it covered them with concrete, paint and anti­slip ­materials—all the trimmings of a proper sports venue, without the typical boundaries. Not that locals seem to mind: Rungjaturapat says the first two fields, which opened earlier this year, are packed with kids as soon as school lets out. This December, AP Thailand plans to open a third.
  • The Headset Leading a Virtual Revolution

    sony-playstation-vr
    Lucas Zarebinski for TIME
    PlayStation VR / $400
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    In order to access the most cutting-edge virtual reality, people typically have to shell out thousands of dollars—not just for a headset (like the $800 HTC Vive), but for a computer that’s powerful enough to support it. Sony’s PlayStation VR, by contrast, is designed to work with a console that millions of people already own: the PlayStation 4. That’s a boon for gamers in search of what Sony engineer Richard Marks calls “the most intense, most extreme” action, as well as casual consumers, who now have an easier way to experience VR.
  • Cannabis That Could Replace Pills

    hmbldt-cannabis-vape
    Lucas Zarebinski for TIME
    Hmbldt Vape Pens / $100 each
    Millions of Americans rely on over-the-­counter medicine to treat routine complications such as insomnia and headaches. What if they took hits of pot instead? That’s what California-­based ­Hmbldt is banking on with its new line of vaporizer pens. When inhaled, the pens dispense a dose of cannabis oil that ­Hmbldt says has been chemically engineered to make people feel a certain way—calm, sleepy, relieved of pain—­without getting high. Cannabis-­delivery methods like this one haven’t yet been thoroughly vetted by physicians. But as more states legalize medical marijuana, and more studies show that it does have merits, products like ­Hmbldt’s (now available only in California) could become increasingly commonplace. “This really can help people feel better,” says Jason ­DeLand, the company’s head of strategy.
  • The Ultimate Alarm Clock

    hello-sense-alarm-clock
    Lucas Zarebinski for TIME
    Hello Sense $149+
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    It’s hard to believe that an alarm clock—the cruel, clunky gadget that jolts you awake and ruins your morning—could not only be beautiful but also improve your sleep. That it could gauge the temperature, humidity, light and even air quality in your bedroom to help you engineer a perfect sleep environment. That it could monitor your sleep cycles and wake you when you’re least likely to feel groggy—all thanks to simple voice commands. Indeed, Sense (and its companion pillow sensor) is no ordinary alarm clock. It took hundreds of prototypes to get it right, says James Proud, founder and CEO of Hello, which makes Sense. Early adopters report that using the small glowing orb feels almost as natural as crawling into bed. That was key, says Proud, who adds, “Nobody wants to introduce complexity into their lives, least of all when it comes to sleep.”
  • Tires That Spin In Every Direction

    goodyear-eagle-360
    Goodyear
    Eagle 360 / Developed by Goodyear
    As companies race to develop self-­driving cars, Goodyear is reinventing their wheels. Its spherical concept tire, which debuted in March, allows cars to move in many new ­directions, including sideways into a parallel parking space and at specific angles and speeds to counteract slippery surfaces. The key, says Sebastien Fontaine, an industrial designer at Goodyear, is magnetic levitation: whereas traditional tires are bolted to cars, the Eagle 360s hover beneath them, free from “the limits of [traditional] steering.” To be sure, these tires won’t hit pavement anytime soon: they’re meant for self-­driving cars that are likely at least five years away. In order to shift the status quo, says Fontaine, “we need different companies working with us, together.”
  • A Sleeker, Smarter Toothbrush

    quip-toothbrush
    Lucas Zarebinski for TIME
    Quip $25+
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    When it comes to dental hygiene, most Americans are slackers: 1 in 2 don’t brush twice a day, and 3 in 4 don’t replace their bristles every three months, no matter how many times they’re warned of the risks (which include cavities and gum disease). “We needed to get people to care a lot more,” says designer Simon Enever. So he and partner Bill May set out to make brushing feel more rewarding. The result is Quip, a simple, affordable, battery-­powered toothbrush that works like its counterparts from Oral-B and ­Sonicare—a two-­minute timer vibrates every 30 seconds, reminding users to switch ­positions—but looks and feels like something you’d find in an Apple store; customers can even opt for a matte metallic finish. “It’s a nicer experience,” says Enever, who adds that he’s already working on his next design challenge: getting you to floss.
  • Dishes That Work Around Cognitive Decline

    eatwell-assistive-tableware
    Lucas Zarebinski for TIME
    Eatwell Assistive Tableware / $60+
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    After her late grandmother was diagnosed with Alzheimer’s, Sha Yao felt helpless. It was especially frustrating, she recalls, to sit with her during meals while she struggled to perform basic functions, like using silverware without spilling. “There was nothing I could do,” Yao says. Inspired by her grandmother’s plight, Yao created Eatwell Assistive Tableware, a dining set designed to make mealtime easier for people with Alzheimer’s and other diseases that affect brain and body function. (Among the design hacks: using bright colors to help people distinguish their plates from their food and putting wide rubber bases on the cups to prevent spills.) The goal, Yao says, is to “bring back the joy of sharing a meal together.”
  • The All-Purpose Shelter

    https://timedotcom.files.wordpress.com/2016/11/better-shelters-ikea-nepal.jpg
    Better Shelter
    Better Shelter / Co-developed by The Ikea Foundation
    Last year, Ikea made headlines when its philanthropic arm, the Ikea Foundation, helped launch Better Shelter, a line of temporary ­houses—­equipped with features like door locks and solar ­panels—that could be shipped flat and assembled in under four hours, much like the retailer’s popular furniture. But now that the U.N. High Commissioner for Refugees has helped send more than 16,000 of these units all over the world, they’ve taken on a life of their own. Just as DIY experts have found ways to remodel Ikea staples into expensive-­looking furniture, refugees and aid agencies are turning Better Shelter structures into hospitals, reception areas and more. In Greece and on its border with Macedonia, the shelters are being linked together and used as early-­childhood-­development centers; in Djibouti, their walls have been retrofitted with “air conditioners” (plastic bottles cut in half to facilitate air flow). Now designers are trying to revamp the Better Shelters to allow for even more flexibility. After all, says Johan Karlsson, managing director of Better Shelter, “we cannot design a one-for-all shelter.”
    Correction: The original version of this story misstated Johan Karlsson’s employer. He is the managing director of Better Shelter.
  • A Stronger, Softer Hair Dryer

    dyson-supersonic-hairdryer
    Lucas Zarebinski for TIME
    Dyson Supersonic $399
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    James Dyson has famously streamlined all kinds of air-centric appliances, most notably vacuums and fans. Now he has set his sights on the hair dryer. Unlike traditional models, which Dyson dismisses as “noisy, heavy and not that fast,” the Supersonic does its job with remarkable efficiency. It’s quiet, thanks to a tiny, jet-engine-like motor that reaches 110,000 revolutions per minute (making it ultrasonic and therefore inaudible to the human ear). It’s fast, thanks to a design that multiplies air flow. And it’s consistently gentle, thanks to a sensor mechanism that keeps hot blown air at one of three exact degree settings. This is hair drying as Dyson thinks it should be, even if it comes at a cost. “We never design down to a price,” he says.
  • Sweet Potatoes That Could Save Lives

    sweet-potatoes
    Benjamin Rakotoariso
    The Orange-Fleshed Sweet Potato / Developed by The International Potato Center (CIP) and Harvestplus
    In sub-Saharan Africa, vitamin A deficiency afflicts more than 43 million children under age 6, leaving them vulnerable to blindness, malaria and more. It’s inefficient to provide entire countries with pills, so plant scientists from HarvestPlus and the CIP are helping countries grow their own ­solutions—in the form of sweet potatoes. The key is biofortification, or cross-­breeding locally grown sweet potatoes with versions rich in vitamin A, so that over time the crops naturally get better at addressing the deficiency. Plant scientists have also bred them to be more resistant to droughts (as Maria Andrade did in Mozambique) and viruses (as Robert Mwanga did in Uganda). This year, Andrade and Mwanga shared the World Food Prize for their work, alongside agricultural economist Jan Low and HarvestPlus founder Howarth Bouis. Sweet potatoes may once have been seen as “a crop of the poor,” says Low, who’s helping to bring the super-spuds to more countries. Now they’re “a healthy crop for all.”
  • A Drone With Mass Appeal

    dji-mavic-pro-drone
    Lucas Zarebinski for TIME
    Dji Mavic Pro $999
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    In recent years, drones have become smarter flyers, faster racers and better photographers. But for the most part, they’re still too big and bulky to carry around comfortably, which can turn off more-­casual consumers. Not so with DJI’s Mavic Pro, which debuted in September; it’s got all the trimmings of a state-of-the-art drone—obstacle-avoidance technology, a 4K camera and the ability to track subjects while ­flying—but it can also fold down to the size of a loaf of bread, smaller than any of its competitors. Realizing that goal required DJI’s engineering team to “rethink all the aspects” of a typical drone, says Darren Liccardo, who helped lead the project. But ultimately, he adds, the effort paid off: because of its smaller size, the Mavic Pro is more nimble and less prone to ­accidents—yet another selling point that could attract new users.
  • The No-Touch Thermometer

    arc-instatemp-thermometer
    Lucas Zarebinski for TIME
    Arc InstaTemp / $40 (for the InstaTemp) and $350 (for the InstaTemp MD)
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    Anyone who has ever had a sick child knows what a hassle it can be to take someone’s temperature using the traditional ­method—­slipping a thermometer under her tongue, getting her to sit still for minutes at a time and hoping that whatever reading you get is accurate. That’s why, in recent years, many brands have started to make no-touch thermometers, which use infrared technology to measure core body temperature quickly and precisely. But one model stands out both for its design and its efficacy: Arc’s Insta­Temp (and its more precise, clinical version, InstaTemp MD), which was recently approved by the FDA. Once the device is placed roughly an inch from a patient’s forehead, it spits out a temperature in 2.5 ­seconds—­coded red, yellow or green, depending on the reading. “If you can take a temperature this way, why would you do it any other way?” says Irwin Gross, CEO of Arc, which is marketing the Insta­Temp devices to consumers and health care professionals alike. “We think this is the way all temperatures will be taken in the future.”
  • The Artificial Pancreas

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    Medtronic
    Minimed 670g / Developed by Medtronic
    In order for people with diabetes to stay healthy, they must continually check their blood sugar and adjust it with insulin or snacks. Medtronic aims to render this tedious process obsolete with its MiniMed 670G, a.k.a. the “artificial pancreas,” which has been in development for years but was only recently approved by the FDA. (It will be commercially available next year.) Once users attach the iPod-size device to their body, it measures their blood-­sugar levels every five minutes, providing more insulin or withholding it as needed. For now, they still need to manually request a dose after they eat. But Medtronic is working on a fully automated version, which Fran Kaufman, chief medical officer of the company’s diabetes group, says she hopes will help the 1.25 million people living with Type 1 diabetes “spend less time managing their disease and more time enjoying life.”
  • China’s ‘Heavenly’ Space Station

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    Xinhua News Agency—Getty Images
    Tiangong-2 / Developed by China’s National Space Agency
    When China’s newest astronauts, Jing Haipeng and Chen Dong, arrived in orbit earlier this year, they docked at some impressive digs. Specifically: the orbital laboratory Tiangong-2 (Heavenly Palace 2), which is more than 34 ft. long and nearly 14 ft. wide and includes an exercise area and a medical-­experiment bay. Yes, that’s all modest compared with the multimodule International Space Station (ISS), which is roughly the size of a football field, but it’s a remarkable machine all the same. China, after all, built Tiangong-2 on its own, just over a decade after launching its first man into space; the ISS is a collaboration among 15 nations, including space veterans like the U.S. and Russia. China’s next move: launching the core module for a much bigger space station, set to happen sometime in 2018.
  • A Prosthesis That’s Built To Play

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    Lucas Zarebinski for TIME
    IKO / Developed by Carlos Arturo Torres
    By design, most prostheses aren’t fun—they’re built to fill a utilitarian need. And while that’s fine for adults, who need to work, it can be tough on kids, who want to play along with their friends. Enter Iko, a prosthetic arm built by Carlos Arturo Torres to enable children to replace a lost limb with one that could have come from Inspector Gadget. When they need a hand, they have one. But they can replace it with any number of toy-like attachments, all of which are compatible with Lego products. (Torres developed the device while working at Lego’s experimental Future Lab in Denmark.) Torres is still finalizing distribution details, but his larger hope is that Iko will destigmatize disability—like it did for 8-year-old Dario, an early tester. Before the test, one of Dario’s friends told Torres he felt sorry for Dario, because there were things he couldn’t do. That changed after the friend watched Dario use Iko. “I want one too,” he said.
  • A Crowd-Pleasing Electric Car

    2017-chevrolet-boltev
    Jessica Lynn Walker—Chevrolet
    Chevrolet Bolt / $40,000
    For most buyers, electric vehicles fall into two camps: too expensive (think the $66,000 Tesla Model S) and too limited (the Nissan Leaf gets just 100 miles per charge). General Motors aims to bridge that gap with the Chevrolet Bolt, which touts crowd-­pleasing features, like more than 200 miles of driving on a single charge, at a relatively low cost. “This is an opportunity to take electric cars mainstream,” GM engineer Pamela Fletcher says of the Bolt, set to launch in December. One industry analyst estimates that GM could sell as many as 80,000 Bolts next year, which would boost the overall market by almost 67%—a small but significant step toward reducing our collective reliance on planet-­warming fossil fuels.
  • A Bracelet That Helps Kids Give Back

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    Lucas Zarebinski for TIME
    UNICEF Kid Power Band / $40
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    One in four American children doesn’t get enough exercise, and 1 in 4 children globally doesn’t get enough food. UNICEF’s Fitbit-like Kid Power Band, designed by San Francisco-based Ammunition, aims to address both problems at once. Its mobile app encourages kids to be physically active with videos from stars like Pink and Alex Morgan. Once they meet step goals, it awards them points, which translate to real food packages that UNICEF sends to malnourished children all over the globe (funded in part by sales of the device). The band “allows kids to feel like they can change the world,” says Rajesh Anandan, who co-created it. Since Kid Power Band’s soft launch in 2014, participants have collectively walked over 7 million miles to feed more than 30,000 severely malnourished children.
  • Headphones That Make Wireless Cool

    apple-airpods
    Lucas Zarebinski for TIME
    Apple Airpods / $159
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    Apple has a history of changing the technological status quo, from digitizing music to making phone screens touch-­sensitive. So when the tech titan announced that its iPhone 7 would not have a 3.5-mm headphone jack, which has been standard on most audio gadgets for decades, it also previewed a compelling alternative. Unlike many of their Bluetooth predecessors, Apple’s AirPods not only have microphones (enabling you to control your phone via Siri) but also can detect when they’re in your ears—­allowing you to automatically pause music, for example, if you pop one out to have a conversation. But their most convenient feature may be automatically pairing with an iPhone, which eliminates the need to dig through settings menus.
  • The Speaker That Speaks Back

    Echo may look like a standard Bluetooth speaker, but at its core lies one of modern society’s holy grails: the ability to talk to your tech. This isn’t a new idea; Apple’s Siri and Microsoft’s Cortana have been around for years. But in many ways, Amazon’s version, Alexa, which is embedded in Echo, is more powerful. Since its 2014 launch, Amazon has greatly expanded Alexa’s functionality; it’s now integrated with dozens of third-party apps, enabling you to call a car (via Uber), turn off lights (via Philips Hue bulbs, among others) or even order pizza (via Domino’s). And Amazon appears determined to keep its edge. It recently launched a junior version of the Echo (the $50 Echo Dot), and it’s working to make Alexa even more intuitive. “We don’t want to teach someone how to speak to Alexa,” says Daren Gill, who heads product and customer experience for Alexa. “They should be able to just speak the way they naturally do.”
  • A Personal Air Purifier

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    Wynd
    Wynd / $154
    No matter where you live and work, you’re breathing in chemicals and pollutants, some more dangerous than others. And while changing that norm will take years, if not decades, of policy work, there are interim solutions. Among them: Wynd, a portable air ­filter—­roughly the size of a water ­bottle—that creates a clean-­climate bubble by sucking up pollutants in your immediate vicinity, including ones that can contribute to cancer and heart disease. “What we breathe matters,” says Ray Wu, creator of Wynd, which raised more than $600,000 on Kickstarter and should be commercially available next year. “We want to enable everyone to enjoy a healthy air environment, no matter where they live or travel.”
    Correction: The original version of this story misstated the price of the Wynd personal air purifier, and the name of the company’s founder. It costs $154, and his name is Ray Wu.
  • Barbies That Look More Like Real Girls

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    Lucas Zarebinski for TIME
    Mattel Barbie dolls / $10 each
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    For 57 years, the world’s most famous doll has been stick-thin, setting an ­unrealistic—and, studies show, ­damaging—beauty standard for generations of young women. That all changed in January when Mattel, faced with slumping sales, decided to make Barbie look more like the girls who play with her. Although the original doll still exists, she now has three additional body types (petite, tall and ­curvy)—a shift that has boosted global sales of the Barbie Fashionista brand by 44%. Of course, society is still a long way from solving its body-image issues; that’s “a heavy burden for [Barbie’s] tiny shoulders,” says Robert Best, a Barbie designer. But the new shapes, along with the new skin tones and hair textures introduced last year, are undeniably a step in the right direction.
http://time.com/4572079/best-inventions-2016/?xid=time_socialflow_twitter